DR. DAVID H PERLMUTTER, MD
Medical Practice at Childrens Pl, Saint Louis, MO

License number
Missouri 2015044366
Category
Medical Practice
Type
Pediatric Gastroenterology
License number
Missouri 2015044366
Category
Medical Practice
Type
Pediatrics
Address
Address
1 Childrens Pl STE C, Saint Louis, MO 63110
Phone
(314) 454-6173
(314) 454-2412 (Fax)

Professional information

David Perlmutter Photo 1

Binding Peptides

US Patent:
5175253, Dec 29, 1992
Filed:
Apr 24, 1991
Appl. No.:
7/690284
Inventors:
Robert J. Fallon - Chesterfield MO
Joseph W. Bulock - St. Peters MO
Steven P. Adams - St. Charles MO
David H. Perlmutter - Clayton MO
Assignee:
Washington University - St. Louis MO
International Classification:
C07K 706, A61K 3700
US Classification:
530330
Abstract:
Novel short peptides of up to about 20 amino acid residues are disclosed that bind to the SEC receptor. These novel peptides preferably are pentapeptides which are synthetic analogs of a pentapeptide domain in the carboxy-terminal fragment of. alpha. sub. 1 -antitrypsin (amino acids 370-374, Phe-Val-Phe-Leu-Met [SEQ ID NO:2]). A preferred binding peptide is Phe-Val-Ala-Leu-Met [SEQ ID NO;6].