Inventors:
William L. Murphy - Ann Arbor MI
Martin C. Peters - Ann Arbor MI
David J. Mooney - Ann Arbor MI
David H. Kohn - Ann Arbor MI
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C08J 934
US Classification:
521 51, 427338, 424484, 424486, 424 9321, 424 932, 514 44
Abstract:
Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.