Inventors:
Joseph R. Nevins - Chapel Hill NC, US
Andrea H. Bild - Salt Lake City UT, US
Guang Yao - Raleigh NC, US
Jeffrey T. Chang - Durham NC, US
Quanli Wang - Durham NC, US
Anil Potti - Chapel Hill NC, US
David Harpole - Durham NC, US
Johnathan M. Lancaster - Tampa FL, US
Andrew Berchuck - Chapel Hill NC, US
John A. Olson - Chapel Hill NC, US
Jeffrey R. Marks - Hillsborough NC, US
Mike West - Durham NC, US
Holly Dressman - Durham NC, US
International Classification:
A61K 39/395, C12Q 1/68, C40B 30/00, A61K 31/4709
US Classification:
4241341, 435 6, 506 7, 514314
Abstract:
The disclosure relates to identifying deregulated pathways in cancer. In certain embodiments, the methods of the disclosure can be used to evaluate therapeutic agents for the treatment of cancer.