Inventors:
David Avigan - Boston MA, US
Donald Kufe - Wellesley MA, US
International Classification:
A61K 39/00, C12N 5/24, C12N 15/09, A61P 35/00, A61P 35/02, G01N 33/574
US Classification:
4242771, 435346, 435455, 435 723, 4241841
Abstract:
The invention is concerned with fusions of dendritic cells and with tumor or cancer cells. Also provided are methods of making and using these cell fusions, including methods of adoptive immunotherapy as well as methods of stimulating anti-tumor immunity using fused cells and anti-CD3/CD28 antibodies.