DAVID DRISCOLL
Broker in East Bridgewater, MA
License number
Massachusetts 66298
Issued Date
Jun 1, 1985
Expiration Date
Jun 18, 2003
Type
Salesperson
Address
Address
East Bridgewater, MA 02324
Professional information
Omega-3 Enriched Fish Oil-In-Water Parenteral Nutrition Emulsions
US Patent:
2012004, Feb 16, 2012
Filed:
Mar 11, 2010
Appl. No.:
13/255828
Inventors:
David F. Driscoll - Bridgewater MA, US
Assignee:
STABLE SOLUTIONS LLC - Goleta CA
International Classification:
A61K 31/685, A61P 29/00, A61P 9/10, A61P 1/16, A61P 37/02, A61K 31/20, A61P 11/00
US Classification:
514 78, 514560
Abstract:
An emulsion is provided including: an oil component and a water component, the oil component including: fish oil triglycerides in an amount of about 60% to about 90% based on the weight of the oil component; wherein the fish oil triglycerides include omega-3 fatty acids, expressed as triglycerides, in an amount of at least 60%, based on the total weight of the fatty acids of the fish oil triglycerides; wherein the fish oil triglycerides include a total amount of EPA and DHA, expressed as triglycerides, of at least 45%, based on the total weight of the fatty acids of the fish oil triglycerides; and, at least one medium-chain triglyceride, wherein a total amount of the at least one medium-chain triglyceride is from about 10% to about 40% based on the weight of the oil component.
Particle Size Distribution Profiles And Use Thereof To Adjust A Dispersion Characteristic
US Patent:
2012031, Dec 20, 2012
Filed:
Nov 10, 2010
Appl. No.:
13/509398
Inventors:
David F. Driscoll - Bridgewater MA, US
David F. Nicoli - Goleta CA, US
David F. Nicoli - Goleta CA, US
International Classification:
G01N 15/02, G01N 15/06
US Classification:
73 6171, 356335
Abstract:
A method for identifying an improved particle size distribution profile of a dispersion, the method including: (a) providing a dispersion comprising a liquid and particles dispersed in the liquid; (b) measuring a particle size distribution of the dispersion, resulting in a first particle size distribution profile; (c) adjusting at least one parameter associated with the dispersion; (d) measuring a dispersion characteristic, after adjustment of the at least one parameter; and (e) measuring the particle size distribution of the dispersion after adjustment of the at least one parameter, resulting in a second particle size distribution profile; wherein each of the first and second particle size distribution profiles comprises a plurality of data points of particle concentration values as a function of particle size.
Stability Assessment Of Dispersions And Emulsions
US Patent:
7150996, Dec 19, 2006
Filed:
Jun 27, 2003
Appl. No.:
10/606959
Inventors:
David F. Nicoli - Goleta CA, US
David F. Driscoll - Bridgewater MA, US
Bruce R. Bistrian - Ipswich MA, US
David F. Driscoll - Bridgewater MA, US
Bruce R. Bistrian - Ipswich MA, US
Assignee:
Stable Solutions, Inc. - Goleta CA
International Classification:
G01N 33/00
US Classification:
436 69, 436164, 436176, 422 73, 422 681, 73 5301, 73 6143, 73 6148, 73 6171, 73 6441, 73 6443
Abstract:
A method and apparatus for determining the stability of dispersions and emulsions accelerates the onset of significant particle agglomeration in a sample by stressing the sample by reducing the height of the interparticle potential energy barrier between the particles. This is achieved by adding one or more of three stress factors: changing the pH of the sample to reduce the surface charge on the particles; adding an adsorbing electrolyte so that ions of the appropriate charge are adsorbed onto the surfaces of the particles to reduce the net charge on the particles; and applying a monovalent, divalent, or trivalent salt to partially screen electrostatic repulsions between the charged particles. In a preferred embodiment, the increase in agglomeration is detected with single particle detection, such as SPOS, to generate a PSD from which a figure of merit is derived. Another embodiment detects turbidity or light scattering to generate a value X indicative of the extent of agglomeration.
Omega-3 Enriched Fish Oil-In-Water Parenteral Nutrition Emulsions
US Patent:
8241672, Aug 14, 2012
Filed:
Mar 11, 2009
Appl. No.:
12/382196
Inventors:
David F. Driscoll - Bridgewater MA, US
Assignee:
Stable Solutions LLC - Goleta CA
International Classification:
A61K 35/60, A23D 9/013, A23D 7/00
US Classification:
424523, 426531, 426601, 426602
Abstract:
A composition is provided which includes an enriched fish oil as a lipid source. Also provided is a composition which includes a fatty acid of a fish oil and a medium-chain triglyceride, wherein the composition is an oil-in-water emulsion.
Method Of Mitigating Adverse Drug Events Using Omega-3-Fatty Acids As A Parenteral Therapeutic Drug Vehicle
US Patent:
2011007, Mar 24, 2011
Filed:
Sep 10, 2010
Appl. No.:
12/923257
Inventors:
David F. Driscoll - Bridgewater MA, US
Assignee:
STABLE SOLUTIONS LLC - Goleta CA
International Classification:
A61K 31/202, A61K 31/7048, A61K 31/343, A61K 31/52, A61K 38/13, A61K 31/436, A61K 31/405, A61K 31/407, A61P 29/00, A61P 43/00, A61P 37/04, A61P 35/00, A61P 7/10
US Classification:
514 205, 514 31, 514469, 5142632, 514291, 514420, 514413, 514560
Abstract:
A method of parenterally administering a composition, the method including parenterally administering to a person a composition including at least one omega-3 fatty acid and at least one drug, wherein the at least one omega-3 fatty acid source and the at least one drug are administered simultaneously.
Method Of Mitigating Adverse Drug Events Using Omega-3 Fatty Acids As A Parenteral Therapeutic Drug Vehicle
US Patent:
2012002, Jan 26, 2012
Filed:
Sep 12, 2011
Appl. No.:
13/230316
Inventors:
David F. Driscoll - Bridgewater MA, US
Assignee:
STABLE SOLUTIONS LLC - GOLETA CA
International Classification:
A61K 38/13, A61K 31/232, A61K 31/7048, A61K 31/47, A61K 31/343, A61K 31/52, A61K 31/436, A61K 31/405, A61K 31/407, A61K 31/7036, A61K 31/65, A61K 31/616, A61P 35/00, A61P 25/16, A61P 9/00, A61P 7/10, A61P 37/06, A61P 25/18, A61P 29/00, A61P 9/10, A61P 13/12, A61P 11/00, A61P 1/16, A61P 39/06, A61P 31/00, A61P 31/04, A61P 31/06, A61P 17/02, A61P 9/06, A61K 31/202
US Classification:
514 205, 514560, 514549, 514 31, 514312, 514469, 5142632, 514291, 514420, 514413, 514 40, 514154, 514163
Abstract:
A method of parenterally administering a composition, the method including parenterally administering to a person a composition including at least one omega-3 fatty acid and at least one drug, wherein the at least one omega-3 fatty acid source and the at least one drug are administered simultaneously.
Therapeutic Application Of Parenteral Krill Oil
US Patent:
2012032, Dec 20, 2012
Filed:
Jun 15, 2011
Appl. No.:
13/161101
Inventors:
David F. DRISCOLL - Bridgewater MA, US
International Classification:
A61K 35/56, A61P 39/02, A61P 9/10, A61P 29/00, A61P 31/00, A61K 31/6615, A61P 39/00
US Classification:
424522, 514121
Abstract:
A method of parenterally administering a composition, the method including parenterally administering to a person a composition including krill oil in an oil-in-water emulsion. A parenterally applicable pharmaceutical composition, including an oil-in-water emulsion including a phospholipid obtained from a marine crustacean.
Reagents And Methods For All-In-One Total Parenteral Nutrition For Neonates And Infants
US Patent:
7323206, Jan 29, 2008
Filed:
Mar 4, 2004
Appl. No.:
10/795200
Inventors:
David Driscoll - Bridgewater MA, US
Bruce Bistrian - Upswich MA, US
Bruce Bistrian - Upswich MA, US
Assignee:
B. Braun Medical Inc. - Bethlehem PA
International Classification:
A23D 7/00, A23D 9/00
US Classification:
426602, 426801
Abstract:
Materials and methods for preparing and using All-in-One (“AIO”) formulations suitable for administration to infants and neonates for total parenteral nutrition are provided.
Particle Size-Structured Parenteral Dispersions
US Patent:
2010020, Aug 19, 2010
Filed:
Feb 13, 2009
Appl. No.:
12/379149
Inventors:
David F. Driscoll - Bridgewater MA, US
David F. Nicoli - Goleta CA, US
David F. Nicoli - Goleta CA, US
Assignee:
Stable Solutions LLC - Goleta CA
International Classification:
A61K 9/14
US Classification:
424489
Abstract:
A Drug/Adjuvant Delivery System (D/A DS), and associated method, are disclosed. An exemplary D/A DS system includes a liquid carrier; and a particle-size structured dispersion of solid and/or liquid particles suspended in the liquid carrier.