DAVID CHOOHYUN PAIK
Medical Practice in Cheltenham, PA
License number
Pennsylvania MD051898L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Cheltenham, PA 19012
Personal information
See more information about DAVID CHOOHYUN PAIK at radaris.comName
Address
Phone
105 Darlene Dr, Pittsburgh, PA 15237
7818 Oak Lane Rd, Cheltenham, PA 19012
105 Darlene Dr, Pittsburgh, PA 15237
7818 Oak Lane Rd, Cheltenham, PA 19012
Professional information
Method Of Stabilizing Human Eye Tissue By Reaction With Nitrite And Related Agents Such As Nitro Compounds
US Patent:
8466203, Jun 18, 2013
Filed:
Dec 6, 2007
Appl. No.:
12/517382
Inventors:
David Choohyun Paik - Cheltenham PA, US
Stephen Lewis Trokel - New York NY, US
Stephen Lewis Trokel - New York NY, US
International Classification:
A01N 59/00, A01N 33/18, A01N 33/24, A61K 33/00, A61K 31/045, C12N 5/00, C12N 5/02
US Classification:
514727
Abstract:
A method for stabilizing collagenous eye tissues by nitrite and nitroalcohol treatment. The topical stiffening agent contains sodium nitrite or a nitroalcohol in a buffered balanced salt solution and can be applied to the surface of the eye on a daily basis for a prolonged period. Application of the solution results in progressive stabilization of the corneal and scleral tissues through non-enzymatic cross-linking of collagen fibers. The compounds can penetrate into the corneal stroma without the need to remove the corneal epithelium. In addition, ultraviolet light is not needed to activate the cross-linking process. The resulting stabilization of corneal and scleral tissues can prevent future alterations in corneal curvature and has utility in diseases such as keratoconus, keratectasia, progressive myopia, and glaucoma.