DAVID C MOORE
Engineering in Rockville, MD

License number
Massachusetts 7086
Issued Date
Jun 10, 1955
Expiration Date
Jun 30, 2004
Type
Structural Engineer
Address
Address
Rockville, MD 20855

Professional information

David Moore Photo 1

Director, Cloud Integration Services At Virtustream

Position:
Director, Cloud Integration Services at Virtustream, Senior Virtualization Advisor at InfoStructures
Location:
Washington D.C. Metro Area
Industry:
Information Technology and Services
Work:
Virtustream - Bethesda, MD since Oct 2011 - Director, Cloud Integration Services InfoStructures - Rockville, MD since Oct 2011 - Senior Virtualization Advisor InfoStructures Aug 2010 - Oct 2011 - Senior Engineer Woodrow Wilson International Center for Scholars Oct 2005 - Aug 2010 - Director, IT Support Services Moore Consulting Services, Inc. Sep 1997 - Aug 2010 - President/CEO
Skills:
VMware Infrastructure, VMware, Systems Engineering, Integration, SAN, Virtualization, Cloud Computing, Windows Server, Data Center, Firewalls, Storage, Program Management, Network Security, Disaster Recovery, Linux, Storage Area Networks, Network Architecture, Computer Security, Servers, VDI, High Availability, Security, System Architecture, Microsoft Technologies, IT Management, vSphere, Cloud Computing IaaS, Hybrid Cloud, VMware ESX, ESXi, SRM, NetApp, EMC Storage


David Moore Photo 2

Use Of Tetrahydrobiopterin As A Marker And A Therapeutic Agent For Fabry Disease

US Patent:
8410101, Apr 2, 2013
Filed:
Apr 9, 2010
Appl. No.:
12/757420
Inventors:
Raphael Schiffmann - Rockwell TX, US
Teodoro G. Bottiglieri - Dallas TX, US
Erland Arning - Fort Worth TX, US
David F. Moore - Rockville MD, US
Assignee:
Baylor Research Institute - Dallas TX
International Classification:
A61P 43/00, G01N 33/20
US Classification:
514249, 514 11, 436 98, 4291301, 424 92
Abstract:
Blood and tissue markers of the metabolic status, risk of health complications in Fabry disease patients and as a biomarker to follow the efficacy of treatment in animal models and patients with Fabry disease comprising tetrahydrobiopterin (BH4), precursors and metabolites of BH4, and other related co-factors is disclosed herein. The present invention further describes the use of BH4 therapy as a treatment option for Fabry disease to prevent, slow or reverses vascular cardiac and renal manifestations of Fabry disease.


David Moore Photo 3

Differential Expression Of Molecules Associated With Acute Stroke

US Patent:
2010026, Oct 21, 2010
Filed:
Jul 1, 2010
Appl. No.:
12/829229
Inventors:
ALISON E. BAIRD - BETHESDA MD, US
DAVID F. MOORE - ROCKVILLE MD, US
EHUD GOLDIN - ROCKVILLE MD, US
International Classification:
C40B 30/04, C12Q 1/68, C40B 40/08
US Classification:
506 9, 435 6, 506 17
Abstract:
Methods are provided for evaluating a stroke, for example for determining whether a subject has had an ischemic stroke, determining the severity or likely neurological recovery of a subject who has had an ischemic stroke, and determining a treatment regimen for a subject who has had an ischemic stroke, as are arrays and kits that can be used to practice the methods. In particular examples, the method includes screening for expression in ischemic stroke related genes (or proteins), such as white blood cell activation and differentiation genes (or proteins), genes (or proteins) related to hypoxia, genes (or proteins) involved in vascular repair, and genes (or proteins) related to a specific peripheral blood mononuclear cell (PBMC) response to the altered cerebral microenvironment. Also provided are methods of identifying one or more agents that alter the activity (such as the expression) of an ischemic stroke-related molecule.


David Moore Photo 4

Differential Expression Of Molecules Associated With Acute Stroke

US Patent:
7749700, Jul 6, 2010
Filed:
Jun 17, 2005
Appl. No.:
11/155835
Inventors:
Alison E. Baird - Brooklyn NY, US
David F. Moore - Rockville MD, US
Ehud Goldin - Rockville MD, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
C12Q 1/68, C12M 1/34
US Classification:
435 6, 4352871
Abstract:
Methods are provided for evaluating a stroke, for example for determining whether a subject has had an ischemic stroke, determining the severity or likely neurological recovery of a subject who has had an ischemic stroke, and determining a treatment regimen for a subject who has had an ischemic stroke, as are arrays and kits that can be used to practice the methods. In particular examples, the method includes screening for expression in ischemic stroke related genes (or proteins), such as white blood cell activation and differentiation genes (or proteins), genes (or proteins) related to hypoxia, genes (or proteins) involved in vascular repair, and genes (or proteins) related to a specific peripheral blood mononuclear cell (PBMC) response to the altered cerebral microenvironment. Also provided are methods of identifying one or more agents that alter the activity (such as the expression) of an ischemic stroke-related molecule.


David Moore Photo 5

Differential Expression Of Molecules Associated With Intra-Cerebral Hemorrhage

US Patent:
2010008, Apr 8, 2010
Filed:
Jul 11, 2007
Appl. No.:
12/307910
Inventors:
Alison E. Baird - Brooklyn NY, US
David F. Moore - Rockville MD, US
Ehud Goldin - Rockville MD, US
Kory Johnson - Rockville MD, US
International Classification:
C12Q 1/68, C40B 40/06, C40B 40/10, A61K 49/00
US Classification:
424 91, 435 6, 506 16, 506 18
Abstract:
Methods are provided for evaluating a stroke, for example for determining whether a subject has had a hemorrhagic stroke, determining the severity or likely neurological recovery of a subject who has had a hemorrhagic stroke, and determining a treatment regimen for a subject who has had a hemorrhagic stroke, as are arrays and kits that can be used to practice the methods. In particular examples, the method includes screening for expression of hemorrhagic stroke related genes (or proteins), such as genes (or proteins) involved in suppression of the immune response, genes (or proteins) involved in vascular repair, genes (or proteins) involved in the acute inflammatory response, genes (or proteins) involved in cell adhesion, genes (or proteins) involved in hypoxia, genes (or proteins) involved in signal transduction, and genes (or proteins) involved in the response to the altered cerebral microenvironment. Arrays and kits are provided that can be used in the disclosed methods. Also provided are methods of identifying one or more agents that alter the activity (such as the expression) of a hemorrhagic stroke-related molecule.


David Moore Photo 6

Methods Of Making Iron-Containing Nanoparticles

US Patent:
8383085, Feb 26, 2013
Filed:
Feb 22, 2010
Appl. No.:
12/660230
Inventors:
Torsten Hegmann - Winnipeg, CA
Vinith Yathindranath - Winnipeg, CA
David F. Moore - Rockville MD, US
Johan van Lierop - Winnipeg, CA
Assignee:
University of Manitoba - Winnipeg, Manitoba
International Classification:
A61K 49/10, A61K 9/14
US Classification:
424 932, 424632, 424646, 424489
Abstract:
A method of making iron-containing nanoparticles (e. g. , magnetite nanoparticles) that includes contacting an iron-containing precursor with a reducing agent at a temperature less than 200° C. and allowing the mixture to react to form magnetite nanoparticles.


David Moore Photo 7

In Vivo Brain Elasticity Measurement By Magnetic Resonance Elastography With Vibrator Coil

US Patent:
2007016, Jul 12, 2007
Filed:
Mar 25, 2004
Appl. No.:
10/550757
Inventors:
David Moore - Rockville MD, US
Seth Goldstein - Bethesda MD, US
Randall Pursley - Germantown MD, US
Lalith Talagala - Rockville MD, US
Assignee:
The Government of the United States of America, as represented by The Secretary of Health and Human - Rockville MD
International Classification:
A61B 5/05
US Classification:
600421000
Abstract:
A vibrator coil () is applied to the skull () by adaptation of a commercially available transcranial Doppler monitoring harness () during MR applies mechanical waves in the acoustic waves through the skull to the brain. Utilizing magnetic resonance elastography (MRE), non-invasive estimation of tissue elastic properties in three dimensions occurs. The propagation of the acoustic waves through brain tissue, coupled to phase alteration of voxel isochromats in the presence of applies motion encoding magnetic field gradients allows measurements of brain elasticity.