DAVID BRUTON
Engineering in Enfield, CT
License number
Massachusetts 15311
Issued Date
Sep 23, 1994
Type
Engineer in Training
Address
Address
Enfield, CT 06082
Professional information
Cell Culture Improvements
US Patent:
2008022, Sep 18, 2008
Filed:
Sep 13, 2007
Appl. No.:
11/901274
Inventors:
Itzcoatl A. Pla - Worcester MA, US
Joseph G. Matuck - Worcester MA, US
John C. Fann - Shrewsbury MA, US
Christof Schulz - Ayer MA, US
Nichole A. Roy - Worcester MA, US
David F. Bruton - Enfield CT, US
James McIntire - Castro Valley CA, US
Yu-Hsiang David Chang - Solana Beach CA, US
Thomas Seewoester - Simi Valley CA, US
Joseph G. Matuck - Worcester MA, US
John C. Fann - Shrewsbury MA, US
Christof Schulz - Ayer MA, US
Nichole A. Roy - Worcester MA, US
David F. Bruton - Enfield CT, US
James McIntire - Castro Valley CA, US
Yu-Hsiang David Chang - Solana Beach CA, US
Thomas Seewoester - Simi Valley CA, US
International Classification:
C12Q 1/02, C12N 5/06, C12P 21/00
US Classification:
435 29, 435405, 435 703, 435 691, 435358
Abstract:
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Cell Culture Improvements
US Patent:
2012007, Mar 29, 2012
Filed:
Nov 30, 2011
Appl. No.:
13/308075
Inventors:
Itzcoatl A. Pla - Worcester MA, US
Joseph G. Matuck - Worcester MA, US
John C. Fann - Shrewsbury MA, US
Christof Schulz - Ayer MA, US
Nichole A. Roy - Worcester MA, US
David F. Bruton - Enfield CT, US
James McIntire - Castro Valley CA, US
Yu-Hsiang David Chang - Solana Beach CA, US
Thomas Seewoester - Simi Valley CA, US
Joseph G. Matuck - Worcester MA, US
John C. Fann - Shrewsbury MA, US
Christof Schulz - Ayer MA, US
Nichole A. Roy - Worcester MA, US
David F. Bruton - Enfield CT, US
James McIntire - Castro Valley CA, US
Yu-Hsiang David Chang - Solana Beach CA, US
Thomas Seewoester - Simi Valley CA, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C12P 21/00, C12Q 1/02, C12Q 1/54, C12N 5/071
US Classification:
435 14, 435 703, 435 691, 435 696, 435358, 435 29, 435405, 435406
Abstract:
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.