PROF. DAVID BRIAN KARPF, M.D.
Osteopathic Medicine at Pasteur Dr, Palo Alto, CA

License number
California G45513
Category
Osteopathic Medicine
Type
Endocrinology, Diabetes & Metabolism
Address
Address 2
300 Pasteur Dr, Palo Alto, CA 94305
16215 Rose Ave, Los Gatos, CA 95030
Phone
(650) 723-6961
(510) 293-8815
(510) 293-6853 (Fax)

Professional information

David B Karpf Photo 1

Dr. David B Karpf, Stanford CA - MD (Doctor of Medicine)

Specialties:
Internal Medicine
Address:
Osteoporosis & Metabolic Bone Disease Clinic
300 Pasteur Dr, Stanford 94305
(650) 723-6961 (Phone)
Certifications:
Internal Medicine, 1983
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Osteoporosis & Metabolic Bone Disease Clinic
300 Pasteur Dr, Stanford 94305
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
Education:
Medical School
University Of California, San Diego, School Of Medicine
Graduated: 1980
Cedars Sinai Med Center
Graduated: 1981
Graduated: 1983
UCLA/Cedars Sinai
Graduated: 1985
Ucsf/Va Med Center
Graduated: 1986


David Karpf Photo 2

Dual Specificity Tumor Killing Vectors Driven By The Telomerase Promoter

US Patent:
2003009, May 29, 2003
Filed:
Jul 25, 2002
Appl. No.:
10/206447
Inventors:
John Irving - San Mateo CA, US
David Karpf - Monte Sereno CA, US
J. Schiff - Menlo Park CA, US
International Classification:
A61K048/00, C12N007/00, C12N015/861, C12N007/01
US Classification:
424/093200, 435/320100, 435/456000, 435/235100
Abstract:
It has been discovered that the specificity of multiple transcriptional regulatory elements can be combined to make vector systems that selectively target cancer cells. The promoter for telomerase reverse transcriptase (TERT) can be combined in a remarkably synergistic fashion with another promoter that has expression restricted to cancer cells or a particular tissue type. The two promoters work synergistically for exquisite targeting of the malignant cells—where it causes cell lysis while leaving neighboring healthy cells intact.


David Karpf Photo 3

Methods For Avoiding Edema In The Treatment Or Prevention Of Pparγ-Responsive Diseases, Including Cancer

US Patent:
8288438, Oct 16, 2012
Filed:
Mar 21, 2006
Appl. No.:
11/908952
Inventors:
Martin E. Sanders - Hillsborough CA, US
David B. Karpf - Monte Sereno CA, US
Assignee:
Metabolex, Inc. - Hayward CA
Dia Tex, Inc. - San Antonio TX
International Classification:
A61K 31/20
US Classification:
514559
Abstract:
Compounds, compositions, and methods of avoiding edema while treating or preventing PPARγ-mediated diseases, including cancer, using derivatives and prodrugs are provided.


David Karpf Photo 4

Methods For Avoiding Edema In The Treatment Of Metabolic, Inflammatory, And Cardiovascular Disorders

US Patent:
2008019, Aug 14, 2008
Filed:
Mar 21, 2006
Appl. No.:
11/908954
Inventors:
Martin E. Sanders - Hillsborough CA, US
David B. Karpf - Monte Sereno CA, US
International Classification:
A61K 31/44, A61K 31/216, A61K 31/4192, A61P 3/04, A61P 3/10, A61P 9/00, A61K 31/192
US Classification:
514354, 514533, 514571, 514359
Abstract:
Compounds, compositions, and methods of treating or preventing PPARγ-mediated diseases, including cancer, using phenoxy acetic acid derivatives and prodrugs are provided.


David Karpf Photo 5

Compositions Of 5-Ethyl-2--Pyrimidine

US Patent:
2011031, Dec 29, 2011
Filed:
Jun 21, 2011
Appl. No.:
13/165651
Inventors:
Charles A. McWherter - Hayward CA, US
Robert Louis Martin - Hayward CA, US
David B. Karpf - Monte Sereno CA, US
Brian K. Roberts - Hayward CA, US
Douglas Alan Lorenz - Bend OR, US
Rodney James Ketner - Bend OR, US
International Classification:
A61K 31/506, A61P 3/08, A61P 3/10, A61P 3/00, A61K 9/10, C07D 417/14
US Classification:
424489, 514275, 544324
Abstract:
This invention relates to the field of pharmaceutical chemistry and, more specifically, to pharmaceutical formulations as well as to intermediates used to prepare such formulations and to methods for manufacturing such formulations.