Inventors:
David B. Maclean - Providence RI
David D. Thompson - Gales Ferry CT
International Classification:
A61K 31135, A61K 3800
Abstract:
The present invention provides novel methods of treating or preventing osteoporosis comprising administering to a mammal in need of such treatment an effective amount of a compound of formula I ##STR1## wherein R. sup. 1 and R. sup. 2 may be the same or different provided that, when R. sup. 1 and R. sup. 2 are the same, each is a methyl or ethyl group, and, when R. sup. 1 and R. sup. 2 are different, one of them is a methyl or ethyl group and the other is hydrogen or a benzyl group; or a pharmaceutically acceptable salt thereof; together with a bone resorption inhibiting polyphosphonate, or with parathyroid hormone.