Inventors:
David B. Avner - Highlands Ranch CO, US
Sven Bocklandt - Los Angeles CA, US
James Kehler - Silver Spring MD, US
International Classification:
C12N 15/85, C12N 5/10, C12N 15/12
US Classification:
435463, 536 235, 4353201, 435351
Abstract:
A transgenic cat with a phenotype characterized by the substantial absence of the major cat allergen, Fel d I. The phenotype is conferred in the transgenic cat by disrupting the coding sequence of the target gene with a specialized construct. The phenotype of the transgenic cat is transmissible to its offspring.