DAVID ANDREW LIPSON
Medical Practice in Penn Wynne, PA
License number
Pennsylvania MD065740L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Penn Wynne, PA 19096
Professional information
Equilibration Method For High Resolution Imaging Of Lung Compliance And Distribution Of Functional Residual Capacity
US Patent:
7072706, Jul 4, 2006
Filed:
Feb 8, 2002
Appl. No.:
10/071435
Inventors:
James Baumgardner - Milmont Park PA, US
David Lipson - Wynnewood PA, US
Rahim Rizi - Montgomeryville PA, US
David Roberts - Rosemont PA, US
Mitchell Schnall - Broomall PA, US
David Lipson - Wynnewood PA, US
Rahim Rizi - Montgomeryville PA, US
David Roberts - Rosemont PA, US
Mitchell Schnall - Broomall PA, US
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
A61B 5/55
US Classification:
600420, 600529, 600533, 600538
Abstract:
The present invention offers novel equilibration methods for very high resolution, three-dimensional imaging of imaging of lung compliance and distribution of functional residual capacity (FRC) in the lung using hyperpolarized helium-3 (He) gas (HHe), and collecting local magnetic resonance image data therefrom. Using the present methods permits many functions that have been performed on a regional level for the whole lung using non-polarized helium, to be calculated for the first time from the local MRI measurements of local HHe, such as measuring volume or compliance.
Quantitative Pulmonary Imaging
US Patent:
6915151, Jul 5, 2005
Filed:
Feb 8, 2002
Appl. No.:
10/071434
Inventors:
James Baumgardner - Milmont Park PA, US
David Lipson - Wynnewood PA, US
Rahim Rizi - Montgomeryville PA, US
David Roberts - Rosemont PA, US
Mitchell Schnall - Broomall PA, US
David Lipson - Wynnewood PA, US
Rahim Rizi - Montgomeryville PA, US
David Roberts - Rosemont PA, US
Mitchell Schnall - Broomall PA, US
Assignee:
Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
A61B005/055
US Classification:
600420, 424 93, 324307, 324309
Abstract:
The present invention comprises imaging and quantitative measurement of lung ventilation, particularly in a human lung. Methods for quantitative imaging of lung ventilation, and the further provided systems and algorithmic tools therefore, comprise three primary components: the combined MRI ventilation/perfusion (V/Q) imaging techniques using hyperpolarized helium-3 (He) gas (HHe); the three-dimensional quantitative imaging of absolute lung perfusion (Q) and collection of local magnetic resonance image data therefrom to produce an absolute lung perfusion image data; and the algorithmic co-registration of the two image data sets, (HP-He MRI image of V/Q and MR imaging of quantitative perfusion (Q) in the lung). From the data acquired in the combined data sets and their spatial co-registration, absolute ventilation (V) is computed.