DAVID ALAN KARLIN
Medical Practice in Los Altos, CA
License number
Pennsylvania MD029436E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Los Altos, CA 94022
Pennsylvania
Pennsylvania
Personal information
See more information about DAVID ALAN KARLIN at radaris.comName
Address
Phone
638 Edinburgh St, San Francisco, CA 94112
2856 Aspen Glen Ct, Chula Vista, CA 91914
2350 Walton Rd, Huntingdon Vy, PA 19006
100 Yerba Santa Ave, Los Altos, CA 94022
2301 Crocker Ln, Modesto, CA 95358
Professional information
Use Of Picoplatin To Treat Colorectal Cancer
US Patent:
8168662, May 1, 2012
Filed:
Jul 23, 2009
Appl. No.:
12/508372
Inventors:
David A. Karlin - Los Altos CA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 31/44
US Classification:
514357
Abstract:
The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens. Dosages, dosing schedules, and ancillary treatments are described.
Picoplatin And Amrubicin To Treat Lung Cancer
US Patent:
2011005, Mar 3, 2011
Filed:
Feb 6, 2009
Appl. No.:
12/866710
Inventors:
Ronald A. Martell - San Francisco CA, US
David A. Karlin - Los Altos CA, US
David A. Karlin - Los Altos CA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 31/704, A61P 35/04
US Classification:
514 34
Abstract:
A method for treatment of lung cancer comprising administration of picoplatin and amrubicin, or comprising radiation therapy and picoplatin is provided. A use of picoplatin in conjunction with amrubicin for treatment of lung cancer is provided. The lung cancer can be SCLC or NSCLC. The cancer can be resistant or refractory to treatment or that progresses following cessation of first-line organoplatinum chemotherapy. The treatment can include the administration of picoplatin and amrubicin, optionally in conjunction with a regimen of best supportive care. Multiple doses of the drug or drug combination can be administered.
Use Of Picoplatin And Cetuximab To Treat Colorectal Cancer
US Patent:
2011005, Mar 3, 2011
Filed:
Feb 6, 2009
Appl. No.:
12/866706
Inventors:
David A. Karlin - Los ALtos CA, US
Ronald A. Martell - San Francisco CA, US
Ronald A. Martell - San Francisco CA, US
Assignee:
Poniard Pharmaceuticals Inc. - Seattle WA
International Classification:
A61K 39/395, C12Q 1/02, A61P 35/00
US Classification:
4241331, 435 29
Abstract:
The invention provides a method of treatment of metastatic colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with cetuximab, 5-FU, and leucovorin in a variety of treatment regimens. The invention also provides a use of picoplatin in conjunction with cetuximab, 5-FU, and leucovorin for treatment of metastatic colorectal cancer. The invention further provides kits adapted for administration of picoplatin in conjunction with cetuximab. Also, methods for determining dosage regimens for patients afflicted with a cancer comprising EGFR are provided.
Use Of Picoplatin And Bevacizumab To Treat Colorectal Cancer
US Patent:
2011005, Mar 3, 2011
Filed:
Feb 6, 2009
Appl. No.:
12/866702
Inventors:
Ronald A. Martell - San Francisco CA, US
David A. Karlin - Los Altos CA, US
David A. Karlin - Los Altos CA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 39/395, A61P 35/00, A61P 35/04
US Classification:
4241331
Abstract:
The invention provides a method of treatment of metastatic colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with bevacizumab (Avastin®) and optionally, with 5-FU and leucovorin in a variety of treatment regimens. The invention also provides a use of picoplatin in conjunction with bevacizumab and, optionally, 5-FU and leucovorin, for the treatment of metastatic colorectal cancer.
Use Of Picoplatin To Treat Colorectal Cancer
US Patent:
8173686, May 8, 2012
Filed:
May 13, 2009
Appl. No.:
12/465563
Inventors:
David A. Karlin - Los Altos CA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 31/44
US Classification:
514357
Abstract:
The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens.
Use Of Picoplatin To Treat Colorectal Cancer
US Patent:
2012015, Jun 21, 2012
Filed:
May 12, 2010
Appl. No.:
13/319852
Inventors:
David A. Karlin - Los Altos CA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 39/395, A61P 35/04, A61P 35/00
US Classification:
4241331
Abstract:
The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens.
Use Of Picoplatin To Treat Colorectal Cancer
US Patent:
8168661, May 1, 2012
Filed:
May 12, 2009
Appl. No.:
12/464662
Inventors:
David A. Karlin - Los Altos CA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 31/44
US Classification:
514357
Abstract:
The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens.
Use Of Picoplatin To Treat Prostate Cancer
US Patent:
2012012, May 17, 2012
Filed:
May 12, 2010
Appl. No.:
13/319647
Inventors:
David A. Karlin MD - Los Altos CA, US
Hazel B. Breitz MD - Seattle WA, US
Paul L. Weiden MD - Seattle WA, US
Robert De Jager - Rancho Santa Fe CA, US
Hazel B. Breitz MD - Seattle WA, US
Paul L. Weiden MD - Seattle WA, US
Robert De Jager - Rancho Santa Fe CA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 31/555, A61P 25/00, A61P 35/00, A61K 31/573, A61P 29/00
US Classification:
514171, 514188
Abstract:
The invention provides a method of treatment of metastatic hormone-refractory prostate cancer involving substantially as concurrent administration of picoplatin and docetaxel. Prednisone may also be administered. Dosages and dosing regimens are provided.
Stabilized Picoplatin Dosage Form
US Patent:
2010021, Aug 26, 2010
Filed:
Dec 10, 2009
Appl. No.:
12/635517
Inventors:
Alistair J. Leigh - Seattle WA, US
Ronald A. Martell - San Francisco CA, US
David A. Karlin - Los Altos CA, US
Cheni Kwok - San Mateo CA, US
Christopher A. Procyshyn - Surrey, CA
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Ronald A. Martell - San Francisco CA, US
David A. Karlin - Los Altos CA, US
Cheni Kwok - San Mateo CA, US
Christopher A. Procyshyn - Surrey, CA
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 9/127, A61K 31/555, A61K 39/395, A61K 31/7068, A61P 35/00, A61P 35/02
US Classification:
424450, 514188, 4241331, 514 49
Abstract:
Methods for stabilizing aqueous solutions of picoplatin are provided. Such stable, preferably aseptic solutions are particularly useful for preparing unit dosages of picoplatin for oral or intravenous administration, preferably in combination with at least one additional non-platinum anti-cancer agent.
Combination Therapy For Ovarian Cancer
US Patent:
2010017, Jul 15, 2010
Filed:
Dec 10, 2009
Appl. No.:
12/635534
Inventors:
Ronald A. Martell - San Francisco CA, US
David A. Karlin - Los Altos CA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
David A. Karlin - Los Altos CA, US
Hazel B. Breitz - Seattle WA, US
Paul L. Weiden - Seattle WA, US
Assignee:
Poniard Pharmaceuticals, Inc. - Seattle WA
International Classification:
A61K 9/127, A61P 35/00, A61K 31/704, A61P 17/00
US Classification:
424450, 514 34
Abstract:
The present invention provides a method to treat ovarian cancer by the administration of effective amounts of picoplatin and pegylated liposomal doxorubicin.