Inventors:
Robert Arslanian - Pacifica CA, US
Gary Ashley - Alameda CA, US
Scott Frykman - Hayward CA, US
Bryan Julien - Oakland CA, US
Leonard Katz - Oakland CA, US
Chaitan Khosla - Palo Alto CA, US
Janice Lau - San Mateo CA, US
Peter Licari - Fremont CA, US
Rika Regentin - Hayward CA, US
Daniel Santi - San Francisco CA, US
Li Tang - Foster City CA, US
International Classification:
C12P017/00, C12P017/02, C07D417/02, C 07D 4 7/02
US Classification:
435/117000, 435/252300, 435/123000, 544/333000, 546/148000, 546/167000, 546/281700, 548/204000
Abstract:
Recombinant Myxococcus host cells can be used to produce polyketides, including epothilone and epothilone analogs that can be purified from the fermentation broth and crystallized.