Inventors:
Gary D. Hodgen - Norfolk VA
Robert F. Williams - Norfolk VA
Daniel Grow - Longmeadow MA
Assignee:
The Medical College of Hampton Roads - Norfolk VA
International Classification:
A61K 3800, A61K 3548, A61K 3824, C07K 1459
Abstract:
A method of treating an ovarian estrogen dependent condition such as endometriosis, uterine leiomyomata, PMS or DUB involving the administration of gonadotropin releasing hormone analog and the administration of antiprogestin, which will provide a therapeutic method for long term treatment without rapid loss of bone density, as occurs using GnRH analogs alone.