Inventors:
Matthew L. Tripp - Gig Harbor WA, US
John G. Babish - Brooktondale NY, US
Jeffrey S. Bland - Fox Island WA, US
Gary K. Darland - Port Orchard WA, US
Robert Lerman - Gig Harbor WA, US
Daniel O. Lukaczer - Gig Harbor WA, US
DeAnn J. Liska - Tacoma WA, US
Terrence M. Howell - Jamaica Plain MA, US
Assignee:
Metaproteomics, LLC - San Clemente CA
International Classification:
A01N 65/00
Abstract:
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.