Inventors:
Charles F. Streckfus - Seabrook TX, US
William P. Dubinsky - Houston TX, US
Lenora Bigler - Houston TX, US
Karen A. Storthz - Houston TX, US
Daniel Arreola - Houston TX, US
Assignee:
BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM - Austin TX
International Classification:
G01N 33/68
US Classification:
514789, 436501, 435 792, 435 74
Abstract:
A method of diagnosing a patient's risk of breast cancer comprises measuring in a saliva sample from the patient a concentration of at least a first protein marker, wherein the first protein marker is either ubiquitin or cytochrome p450, to provide a set of test data comprising a concentration value of each protein marker in the saliva sample. The test values are then compared to a reference panel comprising a Reference Control Value and a Reference Breast Cancer Value, and a diagnosis of either increased or decreased risk of breast cancer is determined for the patient based on a result of that comparison. A test kit for identifying a person at increased risk of breast cancer is also provided.