Inventors:
John A. Maples - Miami FL, US
Lori A. Charie - Pembroke Pines FL, US
Daniel James Flagler - Miami FL, US
Rhonda Ann Mills - Pembroke Pines FL, US
Richard Timmons - Miami FL, US
Assignee:
Beckman Coulter, Inc. - Fullerton CA
International Classification:
G01N033/00, G01N001/00
US Classification:
436176, 436 8, 436 18, 436111, 436128, 436130, 436 63, 436 69, 422 61, 2524081
Abstract:
A stabilization reagent composition, particularly desirable for stabilizing blood samples containing platelets, contains reactants that generate multiple species of formaldehyde-ammonium complexes; at least one inhibitor of phosphatase enzymatic activity; and at least one inhibitor of protease enzymatic activity. Blood samples and other tissues are stabilized by this composition. Such stabilized samples are produced by methods for stabilizing the tissue by contacting the sample with the composition.