DANIEL J PRATT
Engineering in Amesbury, MA
License number
Massachusetts 39491
Issued Date
Aug 27, 1996
Expiration Date
Jun 30, 2018
Type
Chemical Engineer
Address
Address
Amesbury, MA 01913
Professional information
Buoyant Polymer Particles For Delivery Of Therapeutic Agents To The Central Nervous System
US Patent:
7923032, Apr 12, 2011
Filed:
Nov 26, 2003
Appl. No.:
10/723626
Inventors:
Daniel Pratt - Amesbury MA, US
Samuel S. MacAusland - Wellesley MA, US
Keith Baker - Danvers MA, US
Samuel S. MacAusland - Wellesley MA, US
Keith Baker - Danvers MA, US
Assignee:
Seacoast Neuroscience, Inc. - Amesbury MA
International Classification:
A61K 9/14, A61K 9/00, A61K 9/10, A61K 31/13, A61K 31/131, A61K 31/14, A61K 31/56, A61K 31/59
US Classification:
424489, 514167, 514169, 514579, 514659, 514728, 514774, 514776, 514781, 514947, 514951
Abstract:
The invention provides compositions and methods for treating a subject who has suffered from a central nervous system disorder. More particularly, the invention provides sustained polymeric drug delivery systems having a polymer particle, a therapeutic agent, and a buoyancy agent for direct delivery of therapeutic agents into the central nervous system.
Methods For Universally Distributing Therapeutic Agents To The Brain
US Patent:
6123956, Sep 26, 2000
Filed:
Jul 9, 1998
Appl. No.:
9/112708
Inventors:
Keith Baker - Danvers MA
Mark Kieras - Newburyport MA
Martin Redmon - Marlborough MA
Daniel Pratt - Amesbury MA
Mark Kieras - Newburyport MA
Martin Redmon - Marlborough MA
Daniel Pratt - Amesbury MA
International Classification:
A61F 202, A61F 950
US Classification:
424426
Abstract:
A method for universally distributing a therapeutic agent, in an encapsulated form, to the brain of a subject using intrathecal administration, excluding the lumbar region, is described. Methods for treating stroke and/or Traumatic Brain Injury (TBI) are also described. The methods involve intrathecal administration into the cerebrospinal fluid of a subject, of a therapeutic agent in an encapsulated form. Pharmaceutical compositions intended for the amelioration of stroke and/or Traumatic Brain Injury (TBI) are also described. The pharmaceutical compositions comprise a therapeutic agent encapsulated in a pharmaceutically acceptable polymer, suitable for injection into the cerebrospinal fluid of a subject suffering from stroke and/or Traumatic Brain Injury (TBI).
Buoyant Polymer Particles For Delivery Of Therapeutic Agents To The Central Nervous System
US Patent:
8367116, Feb 5, 2013
Filed:
Mar 18, 2011
Appl. No.:
13/051331
Inventors:
Daniel Pratt - Amesbury MA, US
Samuel S. Macausland - Wellesley MA, US
Keith Baker - Danvers MA, US
Samuel S. Macausland - Wellesley MA, US
Keith Baker - Danvers MA, US
Assignee:
Seacoast Neuroscience, Inc. - Amesbury MA
International Classification:
A61K 9/00, A61K 9/10, A61K 9/14, A61K 31/13, A61K 31/131, A61K 31/14, A61K 31/56, A61K 31/59
US Classification:
424489, 514167, 514169, 514579, 514659, 514728, 514774, 514776, 514781, 514947, 514951
Abstract:
The invention provides compositions and methods for treating a subject who has suffered from a central nervous system disorder. More particularly, the invention provides sustained polymeric drug delivery systems having a polymer particle, a therapeutic agent, and a buoyancy agent for direct delivery of therapeutic agents into the central nervous system.