Inventors:
Hartmut Kupper - Mutterstadt, DE
Jeffrey D. Kent - Deerfield IL, US
Mary A. Cifaldi - Gurnee IL, US
John L. Perez - Doylestown PA, US
Gerd R. Burmester - Berlin, DE
Philip Mease - Seattle WA, US
Daniel J. Lovell - Cincinnati OH, US
Edward Keystone - Toronto, CA
Arthur Kavanaugh - San Diego CA, US
International Classification:
A61K 39/395, G01N 33/68, A61K 39/09, A61K 39/145, A61P 37/00, A61P 19/02
US Classification:
4241361, 4241581, 436 86, 514 12, 4241331, 4241421, 4242441, 4242091
Abstract:
The invention provides methods, uses and compositions for the treatment of rheumatoid arthritis. The invention describes methods and uses for treating rheumatoid arthritis wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of rheumatoid arthritis in a subject.