DR. DANIEL E. EPNER, M.D.
Osteopathic Medicine in Houston, TX
License number
Texas H2359
Category
Osteopathic Medicine
Type
Medical Oncology
Address
Address
1515 General Oncology UNIT 241, Houston, TX 77030
Phone
(713) 792-1480
(713) 745-6196 (Fax)
(713) 745-6196 (Fax)
Personal information
See more information about DANIEL E. EPNER at radaris.comName
Address
Phone
Houston, TX
110 Turnberry, San Antonio, TX 78230
403 Squires Row, San Antonio, TX 78213
4802 Bellview St, Bellaire, TX 77401
4907 Spruce St, Bellaire, TX 77401
Professional information
See more information about DANIEL E. EPNER at trustoria.com
Daniel Evan Epner, Houston TX
Daniel Evan Epner, Houston TX
Specialties:
Oncologist
Address:
1515 Holcombe Blvd, Houston, TX 77030
Education:
Baylor University, College of Medicine - Doctor of Medicine
Johns Hopkins Hospital - Fellowship - Oncology (Internal Medicine)
Ronald Reagan UCLA Medical Center - Fellowship - Genetics
Ronald Reagan UCLA Medical Center - Residency - Internal Medicine
Parkland Memorial Hospital - Residency - Internal Medicine
Johns Hopkins Hospital - Fellowship - Oncology (Internal Medicine)
Ronald Reagan UCLA Medical Center - Fellowship - Genetics
Ronald Reagan UCLA Medical Center - Residency - Internal Medicine
Parkland Memorial Hospital - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine, American Board of Internal Medicine Sub-certificate in Hospice and Palliative Medicine (Internal Medicine), American Board of Internal Medicine Sub-certificate in Oncology (Internal Medicine)
Daniel E Epner, Houston TX
Daniel E Epner, Houston TX
Specialties:
Internal Medicine, Hematology & Oncology, Medical Oncology, Diagnostic Radiology
Work:
M.D. Anderson Cancer Center
1515 Holcombe Blvd, Houston, TX 77030
1515 Holcombe Blvd, Houston, TX 77030
Education:
Baylor College of Medicine (1986)
Methionine Restriction For Cancer Therapy
Methionine Restriction For Cancer Therapy
US Patent:
2003012, Jul 10, 2003
Filed:
Aug 30, 2002
Appl. No.:
10/231562
Inventors:
Daniel Epner - Houston TX, US
Jeffrey Baxter - Galena OH, US
Jeffrey Kivi - Westerville OH, US
Robert Hards - Delaware OH, US
Jeffrey Baxter - Galena OH, US
Jeffrey Kivi - Westerville OH, US
Robert Hards - Delaware OH, US
International Classification:
A61K038/48, A61K035/78
US Classification:
424/757000, 424/094630
Abstract:
The present invention is directed to methods and compositions regarding induction of apoptosis in a cell and treatment of cancer in an individual wherein methionine deprivation of the cell is followed by methionine repletion of the cell. The methionine deprivation of the cell results in G2 arrest in the cell, leading to DNA damage in the cell. Upon readministration of methionine to the cell, the damaged cell exits G2 arrest and enters into apoptosis. In a specific embodiment, a therapeutic effect is elicited by cycling the patient between a methionine-depleted diet and a normal, methionine-replete diet. The present invention also regards chronic methionine deprivation for treatment of cancer in a human, in addition to methods for methionine restriction as adjunctive therapy for other cancer treatment methods.