DR. DANIEL D SEDMAK, MD
Medical Practice at 10 Ave, Columbus, OH

6103531, Aug 15, 2000

Feb 12, 1999

9/249154

Daniel Sedmak - Columbus OH
Daniel Miller - Hilliard OH
Brian Rahill - Columbus OH
Yingxue Zhang - Columbus OH

Ohio State Research Foundation - Columbus OH

C12N 1563, C12N 510

435455

A method for reducing levels of JAK 1 and thereby blocking the signal transduction pathways that are employed by IFN-. alpha. , IFN-. beta. , and IFN-. gamma. is provided. In one embodiment the method comprises the steps of: providing a cytomegalovirus (CMV) gene product selected from the group consisting of the CMV immediate early gene (IE) products, the CMV early gene (E) products, and combinations thereof; and introducing the CMV gene product or products into cells at levels sufficient to decrease the levels of JAK 1 in the cell. In another embodiment the method comprises the steps of providing a DNA molecule that comprises a CMV IE gene, a CMV E gene, or combinations thereof; introducing the DNA molecule into the cell; and inducing the expression of CMV IE and E genes in the cell, wherein the expression of products encoded by the CMV IE and CMV E genes decreases the levels of JAK 1 in the cell.

2014001, Jan 16, 2014

Sep 17, 2013

14/029154

Daniel D. Sedmak - Columbus OH, US

A01B 1/22, A01B 33/00

172 15, 172 41

Included are embodiments of a power assisted garden tool. Some embodiments include a handle and an interchangeable tool implement including a garden tool end, a connection end, and an impact platform. Similarly, some embodiments include a drive mechanism coupled to the handle, the drive mechanism including a power source, a motor that provides rotational motion to a rotary shaft, and a piston coupled to the rotary shaft, the piston exhibiting reciprocating motion from the rotational motion, the piston making contact with the interchangeable tool implement, such that the reciprocating motion of the piston causes motion of the interchangeable tool implement.

8579040, Nov 12, 2013

Oct 14, 2010

12/904410

Daniel D. Sedmak - Columbus OH, US

A01B 35/00

172 40, 172 41, 172371

Included are embodiments of a power assisted garden tool. Some embodiments include a handle and an interchangeable tool implement including a garden tool end, a connection end, and an impact platform. Similarly, some embodiments include a drive mechanism coupled to the handle, the drive mechanism including a power source, a motor that provides rotational motion to a rotary shaft, and a piston coupled to the rotary shaft, the piston exhibiting reciprocating motion from the rotational motion, the piston making contact with the interchangeable tool implement, such that the reciprocating motion of the piston causes motion of the interchangeable tool implement.

7993271, Aug 9, 2011

May 17, 2007

11/750161

Jun Liu - Columbus OH, US
Mauro Ferrari - Dublin OH, US
Stanislav I. Rokhlin - Columbus OH, US
Daniel D. Sedmak - Columbus OH, US

The Ohio State University - Columbus OH

A61B 8/00

600437, 600442, 600446

A system and method for screening tissue is provided. The system provides a computer-based system for distinguishing between normal and potentially abnormal tissue. The system includes computer components for generating and receiving ultrasonic waves, for storing a tissue model, and for analyzing received ultrasonic waves in the context of the tissue model.

2004006, Apr 1, 2004

Sep 20, 2002

10/251309

Jun Liu - Columbus OH, US
Mauro Ferrari - Dublin OH, US
Stanislav Rokhlin - Columbus OH, US
Daniel Sedmak - Columbus OH, US

A61B008/14

600/457000

A system and method for screening tissue is provided. The system provides a computer-based system for distinguishing between normal and potentially abnormal tissue. The system includes computer components for generating and receiving ultrasonic waves, for storing a tissue model, and for analyzing received ultrasonic waves in the context of the tissue model.