Inventors:
Duane Miller - Germantown TN, US
Gabor Tigyi - Memphis TN, US
James Dalton - Columbus OH, US
Vineet Sardar - Cordova TN, US
Don Elrod - College Station TX, US
Huiping Xu - Memphis TN, US
Daniel Baker - Memphis TN, US
Dean Wang - Memphis TN, US
Karoly Liliom - Budapest, HU
David Fischer - Plymouth MA, US
Tamas Virag - Memphis TN, US
Nora Nusser - Memphis TN, US
International Classification:
A61K031/675, A61K031/663, C07F009/28
US Classification:
514091000, 514102000, 548112000, 558158000
Abstract:
The present invention relates to compounds according to formula (I) as disclosed herein as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including inhibiting LPA activity on an LPA receptor, modulating LPA receptor activity, treating cancer, enhancing cell proliferation, and treating a wound.