Inventors:
Stephen Calderwood - Wellesley MA, US
Ji Choi - Seon Gnam-Si, KR
Costi Sifri - Charlottesville VA, US
Laurence Rahme - Brookline MA, US
Frederic Ausubel - Newton MA, US
International Classification:
A61K039/02, C12N001/21, C12N015/74
US Classification:
435252340, 424200100, 530350000, 435069300, 435320100
Abstract:
Disclosed are bacterial virulence polypeptides and nucleic acid sequences (e.g., DNA) encoding such polypeptides, and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial or bacteriostatic compounds.