Inventors:
Charles R. Spillert - West Orange NJ
Corinne Devereux - Bronxville NY
Eric J. Lazaro - Jersey City NJ
Assignee:
University of Medicine & Dentistry of N.J. - Newark NJ
International Classification:
A61K 31635, A61K 31505
Abstract:
There is disclosed a process for prolonging recalcification, prothrombin and thrombin times of human plasma which comprises administering to a warm-blooded animal a composition selected from the group consisting of 5-methyl-3-sulfanilamidoisoxazole, a salt of 5-methyl-3-sulfanilamidoisoxazole with a pharmaceutically acceptable base, 2,4-diamino-5-(3,4,5-trimethoxybenzyl) pyrimidine, a salt of 2,4-diamino-5-(3,4,5-trimethoxybenzyl) pyrimidine with a pharmaceutically acceptable acid and mixtures thereof.