DR. CLAYTON MATTHEW BULLOCK, MD, PHD
Psychiatric at Poinsettia Pl, Los Angeles, CA
License number
California A94641
Category
Psychiatric
Type
Psychiatry
Address
Address
1152 N Poinsettia Pl #7, Los Angeles, CA 90046
Phone
(323) 632-8144
Personal information
See more information about CLAYTON MATTHEW BULLOCK at radaris.comName
Address
Phone
459 Joost Ave, San Francisco, CA 94127
13132 Cortina, Tustin, CA 92782
2106 Palo Verde Rd, Irvine, CA 92612
1154 Poinsettia Pl, West Hollywood, CA 90046
Professional information
See more information about CLAYTON MATTHEW BULLOCK at trustoria.com
Screening And Therapeutic Methods For Treating Circadian Rhythm Disorders
Screening And Therapeutic Methods For Treating Circadian Rhythm Disorders
US Patent:
2006017, Aug 3, 2006
Filed:
Jan 31, 2005
Appl. No.:
11/048649
Inventors:
Clayton Bullock - West Hollywood CA, US
Jerome Siegel - Northride CA, US
Jerome Siegel - Northride CA, US
International Classification:
A61K 38/17
US Classification:
514012000
Abstract:
The invention provides a method for screening for a compound for modulating circadian rhythm. The method involves (a) providing a compound that is a Prokineticin 2 (PK2) receptor antagonist or agonist; and (b) determining the ability of the compound to modulate one or more indicia of circadian rhythm function, wherein a compound that modulates one or more indicia of circadian rhythm function is identified as a compound for modulating circadian rhythm. The invention also provides a mouse PK2 receptor nucleic acid, polypeptide and related compositions. Further provided is a method for modulating circadian rhythm of an animal, which involves administering an effective amount of a PK2 receptor antagonist or agonist to an animal. Also provided is an isolated nucleic acid comprising a PK2 gene promoter operatively linked to a heterologous nucleotide sequence.