CLARK WILLIAM SMITH
Pilots at Torrington Rd, Kalamazoo, MI
License number
Michigan A2535268
Issued Date
Sep 2016
Expiration Date
Sep 2018
Category
Airmen
Type
Authorized Aircraft Instructor
Address
Address
6429 Torrington Rd, Kalamazoo, MI 49009
Professional information
Chairman Of The Board At Proteos
Position:
Chairman of the Board at Proteos
Location:
Kalamazoo, Michigan Area
Industry:
Biotechnology
Work:
Proteos
since Oct 2010
-
Chairman of the Board
Proteos
Nov 2003 - Oct 2010
-
Cofounder & CEO
Pharmacia, USA
2002 - 2003
-
Sr. Director Global Res. Site Operations
Pharmacia
1999 - 2003
-
Sr. Director Res. Site Operations
Upjohn Co/Pharmacia & Upjohn/Pharmacia
1983 - 1999
-
Director of Protein Sciences
Upjohn Co
1979 - 1983
-
Scientist
Education:
Cornell University 1973 - 1975
none, Chemistry,biochemistry University of Arizona 1967 - 1973
Ph.D., Chemistry University of Nevada-Reno 1963 - 1967
B.S. in Chemistry, Chemistry
none, Chemistry,biochemistry University of Arizona 1967 - 1973
Ph.D., Chemistry University of Nevada-Reno 1963 - 1967
B.S. in Chemistry, Chemistry
Skills:
Biochemistry
Substituted Tetronic Acids Useful For Treating Hiv And Other Retroviruses
US Patent:
6060600, May 9, 2000
Filed:
Sep 17, 1997
Appl. No.:
8/913463
Inventors:
Robert A. Chruscial - Portage MI
Linda L. Maggiora - Kalamazoo MI
Suvit Thaisrivongs - Kalamazoo MI
James M. Tustin - Richland MI
Clark W. Smith - Kalamazoo MI
Ruben A. Tommasi - Whitehouse Station NJ
Paul A. Aristoff - Kalamazoo MI
Harvey I. Skulnick - Kalamazoo MI
W. Jeffrey Howe - Kalamazoo MI
Linda L. Maggiora - Kalamazoo MI
Suvit Thaisrivongs - Kalamazoo MI
James M. Tustin - Richland MI
Clark W. Smith - Kalamazoo MI
Ruben A. Tommasi - Whitehouse Station NJ
Paul A. Aristoff - Kalamazoo MI
Harvey I. Skulnick - Kalamazoo MI
W. Jeffrey Howe - Kalamazoo MI
Assignee:
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
C07D491107, C07D49102, C07D30700
US Classification:
546 16
Abstract:
This application discloses novel tetronic acids for the treatment of AIDS and other diseases caused by retroviruses.
Substituted Tetronic Acids Useful For Treating Hiv And Other Retroviruses
US Patent:
5977169, Nov 2, 1999
Filed:
Jul 28, 1997
Appl. No.:
8/604937
Inventors:
Robert A. Chrusciel - Portage MI
Linda L. Maggiora - Kalamazoo MI
Suvit Thaisrivongs - Kalamazoo MI
James M. Tustin - Richland MI
Clark W. Smith - Kalamazoo MI
Ruben A. Tommasi - Whitehouse Station NJ
Paul A. Aristoff - Kalamazoo MI
Harvey I. Skulnick - Kalamazoo MI
W. Jeffrey Howe - Kalamazoo MI
Gordon L. Bundy - Portage MI
Linda L. Maggiora - Kalamazoo MI
Suvit Thaisrivongs - Kalamazoo MI
James M. Tustin - Richland MI
Clark W. Smith - Kalamazoo MI
Ruben A. Tommasi - Whitehouse Station NJ
Paul A. Aristoff - Kalamazoo MI
Harvey I. Skulnick - Kalamazoo MI
W. Jeffrey Howe - Kalamazoo MI
Gordon L. Bundy - Portage MI
International Classification:
A61K 3134, A61K 31335, A61K 31415, A61K 31505
US Classification:
514473
Abstract:
This invention comprises novel substituted tetronic acid type compounds, 2, 4(3H, 5H)-furandiones, that are useful for the inhibition of the HIV protease enzyme. The compounds may be useful for the treatment of a person with AIDS or AIDS related diseases. The compounds may be used in the attempt to retard the further replication of any retrovirus containing the aspartyl protease enzyme. Compounds are represented by the formula below. ##STR1##.