CHUN-YANG FAN, MD
Medical Practice at Markham St, Little Rock, AR
License number
Arkansas E-2323
Category
Medical Practice
Type
Anatomic Pathology
Address
Address
4301 W Markham St #783, Little Rock, AR 72205
Phone
(501) 686-8000
Professional information
Cpg Retrieval Of Dna From Formalin-Fixed Pathology Specimen For Promoter Methylation Analysis
US Patent:
2005019, Sep 8, 2005
Filed:
Sep 23, 2004
Appl. No.:
10/955340
Inventors:
Chun-Yang Fan - Little Rock AR, US
Thomas Brent - Memphis TN, US
Thomas Brent - Memphis TN, US
International Classification:
C12Q001/68, C07H021/04, C12P019/34
US Classification:
435006000, 435091200, 435270000, 536025400
Abstract:
The present invention provides a method, referred to as CpG retrieval, to overcome incomplete bisulfite modification of DNA recovered from formalin-fixed tissue samples. The method involves boiling deparaffinized tissue samples in citrate buffer, followed by DNA extraction for promoter methylation analysis. In general, the extracted DNA is further modified by sodium bisulfite and then subjected to a method of promoter methylation analysis. The present invention also reports that hypermethylation of ataxia-telangiectasia-mutated gene promoter is correlated with decreased overall survival in patient with head and neck squamous cell carcinoma.
Dr. Chun-Yang Fan, Little Rock AR - MD (Doctor of Medicine)
Specialties:
Anatomic Pathology
Address:
4301 W Markham St SUITE 783, Little Rock 72205
(501) 686-8000 (Phone)
(501) 686-8000 (Phone)
Certifications:
Anatomic Pathology, 1999
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
4301 W Markham St SUITE 783, Little Rock 72205
Uams Medical Center
4301 West Markham St, Little Rock 72205
Uams Medical Center
4301 West Markham St, Little Rock 72205
Education:
Medical School
Guangzhou Medical University
McGaw Med Center Of Northwestern
Guangzhou Medical University
McGaw Med Center Of Northwestern
Chun-Yang Y Fan, Little Rock AR
Specialties:
Pathologist
Address:
4301 W Markham St, Little Rock, AR 72205
Education:
Doctor of Medicine
Board certifications:
American Board of Pathology Certification in Anatomic Pathology (Pathology)