CHUANXING QU
Medical Practice in Scotch Plains, NJ
License number
Pennsylvania MT200923
Category
Medicine
Type
Graduate Medical Trainee
Address
Address
2
Scotch Plains, NJ 07076
Pennsylvania
Pennsylvania
Personal information
See more information about CHUANXING QU at radaris.comName
Address
Phone
236 Country Club Ln, Scotch Plains, NJ 07076
920 Nineteen North Dr APT 9, Pittsburgh, PA 15237
Westfield, NJ
117A Rivervale Ct, Scotch Plains, NJ 07076
117 Rivervale Ct, Scotch Plains, NJ 07076
Professional information
See more information about CHUANXING QU at trustoria.com
Heterocyclic Aspartyl Protease Inhibitors
Heterocyclic Aspartyl Protease Inhibitors
US Patent:
2012027, Nov 1, 2012
Filed:
Mar 14, 2012
Appl. No.:
13/420007
Inventors:
Zhaoning Zhu - Plainsboro NJ, US
Brian McKittrick - New Vernon NJ, US
Yuanzan C. Ye - Edison NJ, US
Johannes H. Voight - Cranford NJ, US
Corey O. Strickland - Martinsville NJ, US
Elizabeth M. Smith - Verona NJ, US
Andrew Stamford - Chatham NJ, US
William J. Greenlee - Teaneck NJ, US
Robert D. Mazzola - Stewartsville NJ, US
John P. Caldwell - Ringwood NJ, US
Jared N. Cumming - Garwood NJ, US
Lingyan Wang - East Brunswick NJ, US
Yusheng Wu - New York NY, US
Ulrich Iserloh - Hoboken NJ, US
Xiaoxiang Liu - River Vale NJ, US
Tao Guo - Dayton NJ, US
Thuy X.E. Le - Monmouth Junction NJ, US
Kurt W. Saionz - Cranford NJ, US
Suresh D. Babu - Plainsboro NJ, US
Rachael C. Hunter - Princeton NJ, US
Michelle L. Morris - Lawrenceville NJ, US
Huizhong Gu - Monmouth Junction NJ, US
Gang Qian - Kendall Park NJ, US
Dawit Tadesse - East Windsor NJ, US
Ying Huang - East Brunswick NJ, US
Guoqing Li - Belle Mead NJ, US
Jianping Pan - Monmouth Junction NJ, US
Jeffrey A. Misiaszek - Kenilworth NJ, US
Gaifa Lai - Monmouth Junction NJ, US
Jingqi Duo - Monmouth Junction NJ, US
Chuanxing Qu - Scotch Plains NJ, US
Yuefei Shao - Princeton NJ, US
Brian McKittrick - New Vernon NJ, US
Yuanzan C. Ye - Edison NJ, US
Johannes H. Voight - Cranford NJ, US
Corey O. Strickland - Martinsville NJ, US
Elizabeth M. Smith - Verona NJ, US
Andrew Stamford - Chatham NJ, US
William J. Greenlee - Teaneck NJ, US
Robert D. Mazzola - Stewartsville NJ, US
John P. Caldwell - Ringwood NJ, US
Jared N. Cumming - Garwood NJ, US
Lingyan Wang - East Brunswick NJ, US
Yusheng Wu - New York NY, US
Ulrich Iserloh - Hoboken NJ, US
Xiaoxiang Liu - River Vale NJ, US
Tao Guo - Dayton NJ, US
Thuy X.E. Le - Monmouth Junction NJ, US
Kurt W. Saionz - Cranford NJ, US
Suresh D. Babu - Plainsboro NJ, US
Rachael C. Hunter - Princeton NJ, US
Michelle L. Morris - Lawrenceville NJ, US
Huizhong Gu - Monmouth Junction NJ, US
Gang Qian - Kendall Park NJ, US
Dawit Tadesse - East Windsor NJ, US
Ying Huang - East Brunswick NJ, US
Guoqing Li - Belle Mead NJ, US
Jianping Pan - Monmouth Junction NJ, US
Jeffrey A. Misiaszek - Kenilworth NJ, US
Gaifa Lai - Monmouth Junction NJ, US
Jingqi Duo - Monmouth Junction NJ, US
Chuanxing Qu - Scotch Plains NJ, US
Yuefei Shao - Princeton NJ, US
Assignee:
Pharmacopeia Inc. - La Jolla CA
Schering Corporation - Rahway NJ
Schering Corporation - Rahway NJ
International Classification:
A61K 39/395
US Classification:
4241721
Abstract:
Disclosed are compounds of the formula Ior a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein each variable in Formula 1 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula I. Also disclosed are methods of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic magonist or mantagonist.
Heterocyclic Aspartyl Protease Inhibitors
Heterocyclic Aspartyl Protease Inhibitors
US Patent:
2012023, Sep 13, 2012
Filed:
Mar 9, 2012
Appl. No.:
13/416140
Inventors:
Zhaoning Zhu - Plainsboro NJ, US
Brian McKittrick - New Vernon NJ, US
Yuanzan C. Ye - Edison NJ, US
Johannes H. Voigt - Cranford NJ, US
Corey O. Strickland - Martinsville NJ, US
Elizabeth M. Smith - Verona NJ, US
Andrew Stamford - Chatham NJ, US
William J. Greenlee - Teaneck NJ, US
Robert D. Mozzola - Stewartsville NJ, US
John P. Caldwell - Ringwood NJ, US
Jared N. Cumming - Garwood NJ, US
Lingyan Wang - East Brunswick NJ, US
Yusheng Wu - New York NY, US
Ulrich Iserloh - Hoboken NJ, US
Xiaoxiang Liu - River Vale NJ, US
Tao Guo - Dayton NJ, US
Thuy X. E. Le - Monmouth Junction NJ, US
Kurt W. Saionz - Cranford NJ, US
Suresh D. Babu - Plainsboro NJ, US
Rachael C. Hunter - Princeton NJ, US
Michelle L. Morris - Lawrenceville NJ, US
Huizhong Gu - Monmouth Junction NJ, US
Gang Qian - Kendall Park NJ, US
Dawit Tadesse - East Windsor NJ, US
Ying Huang - East Brunswick NJ, US
Guoqing Li - Belle Mead NJ, US
Jianping Pan - Monmouth Junction NJ, US
Jeffrey A. Misiaszek - Kenilworth NJ, US
Gaifa Lai - Monmouth Junction NJ, US
Jingqi Duo - Monmouth Junction NJ, US
Chuanxing Qu - Scotch Plains NJ, US
Yuefei Shao - Princeton NJ, US
Brian McKittrick - New Vernon NJ, US
Yuanzan C. Ye - Edison NJ, US
Johannes H. Voigt - Cranford NJ, US
Corey O. Strickland - Martinsville NJ, US
Elizabeth M. Smith - Verona NJ, US
Andrew Stamford - Chatham NJ, US
William J. Greenlee - Teaneck NJ, US
Robert D. Mozzola - Stewartsville NJ, US
John P. Caldwell - Ringwood NJ, US
Jared N. Cumming - Garwood NJ, US
Lingyan Wang - East Brunswick NJ, US
Yusheng Wu - New York NY, US
Ulrich Iserloh - Hoboken NJ, US
Xiaoxiang Liu - River Vale NJ, US
Tao Guo - Dayton NJ, US
Thuy X. E. Le - Monmouth Junction NJ, US
Kurt W. Saionz - Cranford NJ, US
Suresh D. Babu - Plainsboro NJ, US
Rachael C. Hunter - Princeton NJ, US
Michelle L. Morris - Lawrenceville NJ, US
Huizhong Gu - Monmouth Junction NJ, US
Gang Qian - Kendall Park NJ, US
Dawit Tadesse - East Windsor NJ, US
Ying Huang - East Brunswick NJ, US
Guoqing Li - Belle Mead NJ, US
Jianping Pan - Monmouth Junction NJ, US
Jeffrey A. Misiaszek - Kenilworth NJ, US
Gaifa Lai - Monmouth Junction NJ, US
Jingqi Duo - Monmouth Junction NJ, US
Chuanxing Qu - Scotch Plains NJ, US
Yuefei Shao - Princeton NJ, US
Assignee:
Pharmacopeia Inc. - La Jolla CA
Schering Corporation - Rahway NJ
Schering Corporation - Rahway NJ
International Classification:
A61K 31/513, A61P 25/28, A61P 31/10, A61P 25/00, A61P 29/00, A61K 39/395, A61P 31/04, A61P 9/00, A61P 33/02
US Classification:
4241721, 514272
Abstract:
Disclosed are compounds of the formula Ior a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein each variable in Formula 1 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula I. Also disclosed are methods of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic magonist or mantagonist.
Heterocyclic Aspartyl Protease Inhibitors
Heterocyclic Aspartyl Protease Inhibitors
US Patent:
2012023, Sep 13, 2012
Filed:
Mar 8, 2012
Appl. No.:
13/415404
Inventors:
ZHAONING ZHU - Plainsboro NJ, US
Brian McKittrick - New Vernon NJ, US
Yuanzan C. Ye - Edison NJ, US
Johannes H. Voigt - Cranford NJ, US
Corey O. Strickland - Martinsville NJ, US
Elizabeth M. Smith - Verona NJ, US
Andrew Stamford - Chatham NJ, US
William J. Greenlee - Teaneck NJ, US
Robert D. Mozzola - Stewartsville NJ, US
John P. Caldwell - Ringwood NJ, US
Jared N. Cumming - Garwood NJ, US
Lingyan Wang - East Brunswick NJ, US
Yusheng Wu - New York NY, US
Ulrich Iserloh - Hoboken NJ, US
Tao Guo - Dayton NJ, US
Thuy X. E. Le - Monmouth Junction NJ, US
Kurt W. Sainoz - Cranford NJ, US
Suresh D. Babu - Plainsboro NJ, US
Rachael C. Hunter - Princeton NJ, US
Michelle L. Morris - Lawrenceville NJ, US
Huizhong Gu - Monmouth Junction NJ, US
Gang Qian - Kendall Park NJ, US
Dawit Tadesse - East Windsor NJ, US
Ying Huang - East Brunswick NJ, US
Guoqing Li - Belle Mead NJ, US
Jianping Pan - Monmouth Junction NJ, US
Jeffrey A. Misiaszek - Kenilworth NJ, US
Gaifa Lai - Monmouth Junction NJ, US
Jingqi Duo - Monmouth Junction NJ, US
Chuanxing Qu - Scotch Plains NJ, US
Yuefei Shao - Princeton NJ, US
Brian McKittrick - New Vernon NJ, US
Yuanzan C. Ye - Edison NJ, US
Johannes H. Voigt - Cranford NJ, US
Corey O. Strickland - Martinsville NJ, US
Elizabeth M. Smith - Verona NJ, US
Andrew Stamford - Chatham NJ, US
William J. Greenlee - Teaneck NJ, US
Robert D. Mozzola - Stewartsville NJ, US
John P. Caldwell - Ringwood NJ, US
Jared N. Cumming - Garwood NJ, US
Lingyan Wang - East Brunswick NJ, US
Yusheng Wu - New York NY, US
Ulrich Iserloh - Hoboken NJ, US
Tao Guo - Dayton NJ, US
Thuy X. E. Le - Monmouth Junction NJ, US
Kurt W. Sainoz - Cranford NJ, US
Suresh D. Babu - Plainsboro NJ, US
Rachael C. Hunter - Princeton NJ, US
Michelle L. Morris - Lawrenceville NJ, US
Huizhong Gu - Monmouth Junction NJ, US
Gang Qian - Kendall Park NJ, US
Dawit Tadesse - East Windsor NJ, US
Ying Huang - East Brunswick NJ, US
Guoqing Li - Belle Mead NJ, US
Jianping Pan - Monmouth Junction NJ, US
Jeffrey A. Misiaszek - Kenilworth NJ, US
Gaifa Lai - Monmouth Junction NJ, US
Jingqi Duo - Monmouth Junction NJ, US
Chuanxing Qu - Scotch Plains NJ, US
Yuefei Shao - Princeton NJ, US
Assignee:
Pharmacopeia Inc. - La Jolla CA
Schering Corporation - Rahway NJ
Schering Corporation - Rahway NJ
International Classification:
A61K 39/395, C07D 239/70, C07F 5/02, C07D 403/10, A61K 31/513, A61K 31/506, C07D 409/04, C07D 409/14, C07D 401/04, C07D 405/14, C07D 417/14, C07D 417/04, C07D 413/14, C07D 413/10, A61K 31/5377, A61P 29/00, A61P 9/00, A61P 25/28, A61P 31/10, A61P 33/02, C07D 495/04, A61P 25/00, A61P 31/04, C07D 239/22
US Classification:
4241721, 544321, 544231, 544229, 514272, 544295, 51425505, 544123, 5142358, 5142102
Abstract:
Disclosed are compounds of the formula Ior a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein each variable in Formula 1 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula I. Also disclosed are methods of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic magonist or mantagonist.
Heterocyclic Aspartyl Protease Inhibitors
Heterocyclic Aspartyl Protease Inhibitors
US Patent:
2008020, Aug 21, 2008
Filed:
Feb 23, 2007
Appl. No.:
11/710582
Inventors:
Zhaoning Zhu - Plainsboro NJ, US
Brian McKittrick - New Vernon NJ, US
Yuanzan Ye - Edison NJ, US
Johannes Voigt - Cranford NJ, US
Corey Strickland - Martinsville NJ, US
Elizabeth Smith - Verona NJ, US
Andrew Stamford - Chatham Township NJ, US
William Greenlee - Teaneck NJ, US
Robert Mazzola - Stewartsville NJ, US
John Caldwell - Ringwood NJ, US
Jared Cumming - Garwood NJ, US
Lingyan Wang - East Brunswick NJ, US
Yusheng Wu - New York NY, US
Ulrich Iserloh - Hoboken NJ, US
Xiaoxiang Liu - River Vale NJ, US
Tao Guo - Dayton NJ, US
Thuy Le - Monmouth Junction NJ, US
Kurt Saionz - Cranford NJ, US
Suresh Babu - Plainsboro NJ, US
Rachael Hunter - Princeton NJ, US
Michelle Morris - Lawrenceville NJ, US
Huizhong Gu - Monmouth Junction NJ, US
Gang Qian - Kendall Park NJ, US
Dawit Tadesse - East Windsor NJ, US
Ying Huang - East Brunswick NJ, US
Guoqing Li - Belle Mead NJ, US
Jianping Pan - Monmouth Junction NJ, US
Jeffrey Misiaszek - Kenilworth NJ, US
Gaifa Lai - Monmouth Junction NJ, US
Jingqi Duo - Monmouth Junction NJ, US
Chuanxing Qu - Scotch Plains NJ, US
Yuefei Shao - Princeton NJ, US
Brian McKittrick - New Vernon NJ, US
Yuanzan Ye - Edison NJ, US
Johannes Voigt - Cranford NJ, US
Corey Strickland - Martinsville NJ, US
Elizabeth Smith - Verona NJ, US
Andrew Stamford - Chatham Township NJ, US
William Greenlee - Teaneck NJ, US
Robert Mazzola - Stewartsville NJ, US
John Caldwell - Ringwood NJ, US
Jared Cumming - Garwood NJ, US
Lingyan Wang - East Brunswick NJ, US
Yusheng Wu - New York NY, US
Ulrich Iserloh - Hoboken NJ, US
Xiaoxiang Liu - River Vale NJ, US
Tao Guo - Dayton NJ, US
Thuy Le - Monmouth Junction NJ, US
Kurt Saionz - Cranford NJ, US
Suresh Babu - Plainsboro NJ, US
Rachael Hunter - Princeton NJ, US
Michelle Morris - Lawrenceville NJ, US
Huizhong Gu - Monmouth Junction NJ, US
Gang Qian - Kendall Park NJ, US
Dawit Tadesse - East Windsor NJ, US
Ying Huang - East Brunswick NJ, US
Guoqing Li - Belle Mead NJ, US
Jianping Pan - Monmouth Junction NJ, US
Jeffrey Misiaszek - Kenilworth NJ, US
Gaifa Lai - Monmouth Junction NJ, US
Jingqi Duo - Monmouth Junction NJ, US
Chuanxing Qu - Scotch Plains NJ, US
Yuefei Shao - Princeton NJ, US
International Classification:
A61K 31/506, A61K 31/4178, A61K 31/4245, A61K 31/4439, A61K 31/454, A61K 31/541, A61P 31/00, C07D 233/02, C07D 271/00, C07D 413/14, C07D 409/14, C07D 409/04, C07D 403/06, C07D 401/14, C07D 401/12, C07D 401/10, C07D 401/06, C07D 239/04, A61P 9/00, A61P 25/00, A61K 31/5377, A61K 31/4545, A61K 31/4709, A61K 31/498
US Classification:
514210020, 514222200, 514229200, 514235800, 514249000, 514272000, 514313000, 514318000, 514326000, 514341000, 514389000, 544295000, 544321000, 544066000, 546162000, 546194000, 546210000, 546274400, 546297000, 548314400, 548550000
Abstract:
Disclosed are compounds of the formula I
or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein
Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic magonist or mantagonist.