CHRISTOPHER PAUL CRUM, MD
Medical Practice in Boston, MA

License number
Massachusetts 72572
Category
Medical Practice
Type
Anatomic Pathology
Address
Address 2
75 Brigham And Womens Hospital Department Of Pathology, Boston, MA 02115
111 Cypress St, Brookline, MA 02445
Phone
(617) 732-7510
(617) 582-1200

Professional information

Christopher Paul Crum Photo 1

Christopher Paul Crum, Brookline MA

Specialties:
Pathologist
Address:
111 Cypress St, Brookline, MA 02445
300 Longwood Ave, Boston, MA 02115
75 Francis St, Boston, MA 02115
Education:
University of Virginia, School of Medicine - Doctor of Medicine
New York Presbyterian Hospital-Columbia Presbyterian Center - Fellowship - Ob-Gyn Pathology
University of Virginia Health System - Residency - Pathology
Board certifications:
American Board of Pathology Certification in Anatomic Pathology (Pathology)


Christopher P Crum Photo 2

Dr. Christopher P Crum, Boston MA - MD (Doctor of Medicine)

Specialties:
Anatomic Pathology
Address:
75 Francis St, Boston 02115
(617) 732-7510 (Phone)
335 Clinton Rd, Brookline 02445
75 Francis St, Boston 02115
BRIGHAM AND WOMENS HOSPITAL
75 Francis St, Boston 02115
(617) 732-5500 (Phone)
75 Francis St, Boston 02115
(617) 732-7510 (Phone)
75 Francis St, Boston 02115
BRIGHAM AND WOMENS HOSPITAL
75 Francis St, Boston 02115
(617) 732-5500 (Phone)
BRIGHAM AND WOMENS HOSPITAL
75 Francis St, Boston 02115
(617) 732-5500 (Phone)
Certifications:
Anatomic Pathology, 1980
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
75 Francis St, Boston 02115
75 Francis St, Boston 02115
335 Clinton Rd, Brookline 02445
75 Francis St, Boston 02115
75 Francis St, Boston 02115
BRIGHAM AND WOMENS HOSPITAL
75 Francis St, Boston 02115
BRIGHAM AND WOMENS HOSPITAL
75 Francis St, Boston 02115
BRIGHAM AND WOMENS HOSPITAL
75 Francis St, Boston 02115
Brigham and Women's Hospital
75 Francis St, Boston 02115
Education:
Medical School
Univ Of Va Sch Of Med Hlth Sys
Graduated: 1974
U SC Affil Hosp
University of Virginia Medical Center
Columbia P&S


Christopher Paul Crum Photo 3

Christopher Paul Crum, Boston MA

Specialties:
Pathology, Anatomic Pathology
Work:
Brigham and Women's Hospital
75 Francis St, Boston, MA 02115
Education:
University of Virginia (1974)


Christopher Crum Photo 4

Cell Regulatory Genes, Encoded Products, And Uses Related Thereto

US Patent:
6946256, Sep 20, 2005
Filed:
Mar 29, 2000
Appl. No.:
09/538106
Inventors:
Frank McKeon - Boston MA, US
Annie Yang - Boston MA, US
Massimo Loda - Belmont MA, US
Christopher Crum - Brookline MA, US
Assignee:
President & Fellows of Harvard College - Cambridge MA
The Brigham and Women's Hospital, Inc. - Boston MA
Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:
G01N033/53, A61K039/395
US Classification:
435 71, 436500, 436501, 436512, 4241301, 4241311, 4241341, 4241351
Abstract:
This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to transactivate p53 reporter genes and induce apoptosis. Isotopes of p63 lacking a transactivation domain act as dominant negatives towards the transactivation by p53 and p63.


Christopher Crum Photo 5

Cell Regulatory Genes, Encoded Products, And Uses Related Thereto

US Patent:
2006001, Jan 26, 2006
Filed:
Apr 19, 2005
Appl. No.:
11/109831
Inventors:
Frank McKeon - Boston MA, US
Annie Yang - Boston MA, US
Massimo Loda - Belmont MA, US
Sabina Signoretti - Brookline MA, US
Christopher Crum - Brookline MA, US
International Classification:
G01N 33/53, G01N 33/574, C07H 21/04, C07K 14/82
US Classification:
435007100, 435007230, 530350000, 536023500
Abstract:
Disclosed herein are methods for diagnosing cancer in a biological sample comprising measuring the level of a p63 gene product in the sample.


Christopher Crum Photo 6

H3K27Me3 And Cancer

US Patent:
2012020, Aug 9, 2012
Filed:
Jul 14, 2010
Appl. No.:
13/383106
Inventors:
Karl Munger - Newton MA, US
Christopher Crum - Brookline MA, US
Margaret McLaughlin-Drubin - Jamaica Plain MA, US
Assignee:
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. - Boston MA
International Classification:
A61K 31/4745, A61P 35/00, C12Q 1/68, G01N 33/574, G01N 33/573, G01N 33/566
US Classification:
514293, 435 74, 435 71, 435 612
Abstract:
Methods of diagnosing and monitoring cancers and precancerous lesions associated with human papillomavirus (HPV), by detecting abnormal levels of lysine (K)-specific demethylase 6A (KDM6A), KDM6B, or trimethylated Histone H3 Lys27 (H3K27me3).