Inventors:
Christopher M. Adams - Iowa City IA, US
Steven D. Kunkel - Iowa City IA, US
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
C07C 61/29, C07C 235/82, C07C 69/12, C07D 265/30, C07C 69/757, C07J 53/00
US Classification:
514169, 562403, 514557, 560 6, 514510, 552510, 560194, 560 75, 544154, 5142378, 564188, 514623
Abstract:
In one aspect, the invention relates methods for inhibiting or preventing muscle atrophy or increasing muscle mass by providing to a subject in need thereof an effective amount of ursolic acid, a derivative thereof, or an analog of the ursane scaffold. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.