CHRISTOPHER J HORVATH
Veterinary in Taunton, MA
License number
Massachusetts 3756
Issued Date
Jun 14, 1990
Expiration Date
Feb 28, 2017
Type
Veterinarian
Address
Address
Taunton, MA 02780
Personal information
See more information about CHRISTOPHER J HORVATH at radaris.comName
Address
Phone
56 Winthrop St, Taunton, MA 02780
209 Plain St, Taunton, MA 02780
209 Plain St, Taunton, MA 02780
209 Plain St, Taunton, MA 02780
275 Kendrick Ave, Wellfleet, MA 02667
Professional information
See more information about CHRISTOPHER J HORVATH at trustoria.com
Anti-Ccr2 Antibodies And Methods Of Use Therefor
Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
6352832, Mar 5, 2002
Filed:
Jul 22, 1999
Appl. No.:
09/359193
Inventors:
Gregory J. LaRosa - West Roxbury MA
Christopher Horvath - Taunton MA
Walter Newman - Boston MA
Christopher Horvath - Taunton MA
Walter Newman - Boston MA
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
G01N 3353
US Classification:
435 71, 435 5, 435345, 435343, 4353432, 436548
Abstract:
The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e. g. , human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Recombinant Anti-Ccr2 Antibodies And Methods Of Use Therefor
Recombinant Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
6727349, Apr 27, 2004
Filed:
Feb 3, 2000
Appl. No.:
09/497625
Inventors:
Gregory J. LaRosa - Newton MA
Christopher Horvath - Taunton MA
Walter Newman - Boston MA
S. Tarran Jones - Radlett, GB
Siobhan H. OBrien - Finchley, GB
Theresa OKeefe - Waltham MA
Christopher Horvath - Taunton MA
Walter Newman - Boston MA
S. Tarran Jones - Radlett, GB
Siobhan H. OBrien - Finchley, GB
Theresa OKeefe - Waltham MA
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07K 1600
US Classification:
5303873, 4241301, 4241561, 5303871, 53038823
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e. g. , human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
2013007, Mar 21, 2013
Filed:
Jun 20, 2012
Appl. No.:
13/528407
Inventors:
Gregory J. LaRosa - West Roxbury MA, US
Christopher J. Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Radlett, GB
Siobhan H. O'Brien - Bishops Stortford, GB
Theresa O'Keefe - Waltham MA, US
Christopher J. Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Radlett, GB
Siobhan H. O'Brien - Bishops Stortford, GB
Theresa O'Keefe - Waltham MA, US
International Classification:
C07K 16/28
US Classification:
4241331, 5303873, 536 2353, 4353201, 435328, 435 696, 435375, 4352523, 43525233, 43525231, 43525411, 4352542, 43525423, 4352543, 43525421, 4352544
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
8227211, Jul 24, 2012
Filed:
Sep 23, 2008
Appl. No.:
12/235765
Inventors:
Gregory J. LaRosa - Newton MA, US
Christopher Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Hertfordshire, GB
Siobhan H. O'Brien - Herts, GB
Theresa O'Keefe - Waltham MA, US
Christopher Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Hertfordshire, GB
Siobhan H. O'Brien - Herts, GB
Theresa O'Keefe - Waltham MA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K 39/395, C12N 15/13, C07K 16/00
US Classification:
435 696, 43525231, 43525233, 43525411, 435375, 4241331, 5303873
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e. g. , human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
2008024, Oct 2, 2008
Filed:
Oct 25, 2007
Appl. No.:
11/924153
Inventors:
Gregory J. LaRosa - Newton MA, US
Christopher J. Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Hertfordshire, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Christopher J. Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Hertfordshire, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Assignee:
MILLENNIUM PHARMACEUTICALS, INC. - Cambridge MA
International Classification:
C12N 5/06
US Classification:
435375
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
7442775, Oct 28, 2008
Filed:
Jan 27, 2004
Appl. No.:
10/766610
Inventors:
Gregory J. LaRosa - Newton MA, US
Christopher Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Radlett, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Christopher Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Radlett, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07H 23/00, A61K 39/00, C12N 15/00
US Classification:
5303879, 536 2353, 4353201, 435328
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e. g. , human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
2008026, Oct 30, 2008
Filed:
Oct 25, 2007
Appl. No.:
11/924091
Inventors:
Gregory J. LaRosa - Newton MA, US
Christopher J. Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Hertfordshire, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Christopher J. Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Hertfordshire, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Assignee:
MILLENNIUM PHARMACEUTICALS, INC. - Cambridge MA
International Classification:
C12N 5/06
US Classification:
435375
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
7473421, Jan 6, 2009
Filed:
Jan 27, 2004
Appl. No.:
10/766773
Inventors:
Gregory J. LaRosa - Newton MA, US
Christopher Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Radlett, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Christopher Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Radlett, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
C07K 16/00, A61K 39/02
US Classification:
4241391, 435 696, 435 5
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e. g. , human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
Humanized Anti-Ccr2 Antibodies And Methods Of Use Therefor
US Patent:
7566450, Jul 28, 2009
Filed:
Oct 26, 2007
Appl. No.:
11/924794
Inventors:
Gregory J. LaRosa - Newton MA, US
Christopher J. Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Hertfordshire, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Christopher J. Horvath - Taunton MA, US
Walter Newman - Boston MA, US
S. Tarran Jones - Hertfordshire, GB
Siobhan H. O'Brien - London, GB
Theresa O'Keefe - Waltham MA, US
Assignee:
Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:
A61K 39/395
US Classification:
4241391, 4241421, 4241431
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e. g. , human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Cd18-Binding Antibodies And Use Thereof For Inhibition And Alleviation Of Stenosis-Related Symptoms And Disorders
Cd18-Binding Antibodies And Use Thereof For Inhibition And Alleviation Of Stenosis-Related Symptoms And Disorders
US Patent:
2004010, May 27, 2004
Filed:
Nov 17, 2003
Appl. No.:
10/716028
Inventors:
Christopher Horvath - Taunton MA, US
Assignee:
Millennium Pharmaceuticals, Inc., a Delaware corporation
International Classification:
A61K039/395
US Classification:
424/144100
Abstract:
The invention is based on the discovery that molecules (e.g. a monoclonal antibody or a portion thereof) which bind specifically with the CD18 subunit of a CD18-containing leukocyte cell-surface antigens (e.g. a cell-surface antigen such as Mac-1 which contains both CD18 and a form of CD11) can be used to inhibit, prevent, and alleviate vascular stenotic and restenotic lesions and symptoms and disorders associated with such lesions.