Inventors:
Lisa K. Jennings - Memphis TN, US
Chunxiang Zhang - Memphis TN, US
Larry C. Wadsworth - Knoxville TN, US
Randall R. Bresee - Walland TN, US
Roberto S. Benson - Knoxville TN, US
Christopher P. Stephens - Knoxville TN, US
International Classification:
A61F 2/06, B05D 7/00
Abstract:
The present invention relates to a vascular stent that includes an expandable stent defining an interior compartment, a first polymeric layer exposed to the interior compartment defined by the stent, the first layer comprising an agent that promotes re-endothelialization, an agent that inhibits thrombosis, or a combination thereof, and a second polymeric layer at least partially external of the stent, the second layer being adapted for contacting a vascular surface and being characterized by pores that are substantially impermeable to vascular smooth muscle cell migration. Method of making and using the vascular stent are also disclosed.