Inventors:
Radharani Marik - Baltimore MD, US
Christopher B. Umbricht - Baltimore MD, US
Martha A. Zeiger - Baltimore MD, US
Assignee:
The John Hopkins University - Baltimore MD
International Classification:
C12Q 1/68, C07H 21/04, A61K 31/167, A61P 35/00, A61K 31/4353, A61K 31/165, A61K 31/166, A61K 31/706, A61K 31/593, A61K 31/19
US Classification:
514 43, 435 612, 514167, 536 2433, 514575, 514557, 514300, 514620
Abstract:
The invention features compositions and methods for characterizing the methylation status of the Vitamin D Receptor (VDR) in neoplasia (e.g., breast carcinoma), selecting an appropriate therapy, and treating the neoplasia (e.g., breast carcinoma).