CHRISTOPHER ALBERT SULLIVAN, MD
Medical Practice at Medical Center Blvd, Winston Salem, NC

2009002, Jan 29, 2009

May 30, 2008

12/130614

Christopher A. Sullivan - Winston-Salem NC, US
Steve J. Hodges - Winston-Salem NC, US

Wake Forest University Health Science - Winston-Salem NC

A61F 2/00, A61K 31/7028

424402, 424423, 424426, 514 33

Provided herein are implantable or insertable biomedical devices comprising a substrate and a collagen inhibitor on or in said substrate, and methods of treatment using the same. In some embodiments, the device is an absorbable esophageal or tracheal stent. In some embodiments, the device is a vascular stent. Wound closure devices are also provided herein, including a substrate and a collagen inhibitor on or in the substrate. Also provided are surgical packings, including a substrate and a collagen inhibitor on or in the substrate. A barrier material for preventing adhesions in a subject is further provided, including a preformed or in situ formable barrier substrate and a collagen inhibitor on or in the substrate. An ointment comprising a collagen inhibitor is further provided. Kits comprising the coated substrates are also provided.

2006017, Aug 3, 2006

Feb 1, 2005

11/048097

Anthony Atala - Winston Salem NC, US
Akira Joraku - Winston-Salem NC, US
Christopher Sullivan - Winston-Salem NC, US
James Yoo - Winston Salem NC, US

A61K 8/96, A61K 35/12

424050000, 424093700

The invention is directed to compositions and methods for preparing an artificial oral tissue. The artificial oral tissue is prepared using a biocompatible substrate seeded with salivary gland cells that develop to produce a salivary gland tissue layer with a prototypal salivary system and a prototypal secretory system. The salivary gland cells proliferate, mature and differentiate into a salivary gland structure that are analogous to its in vivo counterpart.

2008013, Jun 5, 2008

Nov 30, 2007

11/948294

Christopher A. Sullivan - Winston-Salem NC, US
Steve J. Hodges - Winston-Salem NC, US

A61B 17/08, A61B 17/04

606219, 606228, 606151, 606213

Provided herein are implantable or insertable biomedical devices comprising a substrate and a collagen inhibitor on or in said substrate, and methods of treatment using the same. In some embodiments, the device is a urethral, ureteral, or nephroureteral catheter or stent. In some embodiments, the device is an absorbable esophageal or tracheal stent. Wound closure devices are also provided herein, including a substrate and a collagen inhibitor on or in the substrate. Also provided are surgical packings, including a substrate and a collagen inhibitor on or in the substrate. A barrier material for preventing adhesions in a subject is further provided, including a preformed or in situ formable barrier substrate and a collagen inhibitor on or in the substrate. Kits comprising the coated substrates are also provided.