Inventors:
Anatoly E. Martynyuk - Gainesville FL, US
Donn M. Dennis - Gainesville FL, US
Nikolaus Gravenstein - Gainesville FL, US
Alexander V. Glushakov - Gainesville FL, US
Viktor Yarotskyy - Gainesville FL, US
Colin Sumners - Gainesville FL, US
Christoph Seubert - Gainesville FL, US
International Classification:
A61K 31/197, A61K 31/451, A61K 31/496, A61K 31/519, A61K 31/5415, A61K 31/551, A61P 25/00, A61P 25/18
US Classification:
514220, 5142275, 5142278, 51425213, 51425941, 514327, 514567
Abstract:
The subject invention pertains to methods of treating mental illnesses or conditions characterized by a decreased function of NMDA receptors and/or excessively enhanced glutamate release and activity of non-NMDA receptors (AMPA and/or kainate). Specifically disclosed are methods utilizing BrPhe, or isomers of analogs thereof, for treating or preventing mental illness or conditions such as schizophrenia.