CHRISTINE LEE BLUMHARDT
Pharmacy in Delaware
License number
Pennsylvania RP029802L
Category
Pharmacy
Type
Pharmacist
Address
Address
2
Delaware
Wayne, PA 19087
Wayne, PA 19087
Professional information
Method Of Treating Insomnia
US Patent:
2012003, Feb 16, 2012
Filed:
Dec 15, 2009
Appl. No.:
13/139881
Inventors:
Gary Cupit - Basking Ridge NJ, US
Anne McCormick - Madison NJ, US
Mary Osbakken - Philadelphia PA, US
Christine Blumhardt - Strafford PA, US
Anne McCormick - Madison NJ, US
Mary Osbakken - Philadelphia PA, US
Christine Blumhardt - Strafford PA, US
Assignee:
SOMNUS THERAPEUTICS, INC. - Bedminster NJ
International Classification:
A61K 31/519, A61P 25/20, A61K 9/00
US Classification:
424400, 5142593
Abstract:
A method of treating insomnia comprising administering to a subject a formulation including zaleplon, wherein the formulation is adapted to release the zaleplon after a lag time of at least about one hour after administration of the formulation, and during which substantially no drug substance is released; provide a time of peak plasma concentration of about 3 hours to about 6 hours after administration; provide an elimination half-life after the time of peak plasma concentration of about 0.5 hours to about 0.3 hours; and provide an area under the curve of about 70 ng·h/mL to about 90 ng·h/mL.