Chirag R Parikh
Physician in Denver, CO
License number
Colorado 38552
Issued Date
Mar 9, 2000
Renew Date
Jun 1, 2003
Expiration Date
May 31, 2005
Type
Physician
Address
Address
University Of Colorado Health, Denver, CO 80262
Professional information
Methods For Detection Of Il-18 As An Early Marker For Diagnosis Of Acute Renal Failure And Predictor Of Mortality
US Patent:
7141382, Nov 28, 2006
Filed:
Oct 12, 2004
Appl. No.:
10/964201
Inventors:
Chirag R. Parikh - Denver CO, US
Charles L. Edelstein - Denver CO, US
Charles L. Edelstein - Denver CO, US
International Classification:
G01N 33/53
US Classification:
435 71, 435 792, 436518
Abstract:
The present disclosure concerns methods of detecting a molecule, interleukin 18, in a sample, and using the detection of IL-18 to predict a condition. In a particular embodiment, the present invention concerns methods of detecting interleukin 18, in a sample, preferably prior to the increase in serum creatinine in a subject predisposed to a condition. In certain embodiments, the methods may comprise obtaining a sample from a subject such as a urine or blood sample and analyzing the sample for the presence or absence of IL-18 to predict a condition for example acute renal failure or organ transplant failure. In another embodiment, the methods may comprise analyzing a sample from a subject for the presence of IL-18 and applying information obtained from analyzing the presence of IL-18 to determine a treatment for a medical condition of the subject.