Inventors:
Cheryl L. Willman - Albuquerque NM, US
Paul Helman - Albuquerque NM, US
Robert Veroff - Albuquerque NM, US
George S. Davidson - Albuquerque NM, US
Shawn B. Martin - Albuquerque NM, US
Susan R. Atlas - Albuquerque NM, US
Erik Andries - Rio Rancho NM, US
Huining Kang - Albuquerque NM, US
Jonathan J. Shuster - Gainesville FL, US
Xuefei Wang - Albuquerque NM, US
Richard C. Harvey - Placitas NM, US
David M. Haaland - Albuquerque NM, US
Jeffrey W. Potter - Albuquerque NM, US
International Classification:
A61K 38/17, C12N 15/12, C07H 21/04, C07K 14/47, A61K 31/711, A61P 35/02, C12N 5/10, C12N 15/85, C12Q 1/68, G01N 33/566
US Classification:
514 12, 536 235, 536 245, 530350, 4353201, 435 6, 435 71, 514 44, 435325
Abstract:
Genes and gene expression profiles useful for predicting outcome, risk classification, cytogenetics and/or etiology in pediatric acute lymphoblastic leukemia (ALL). OPAL1 is a novel gene associated with outcome and, along with other newly identified genes, represent a novel therapeutic targets.