Inventors:
Chen Hsing Hsu - Ann Arbor MI, US
Shou Shan Chiang - Taipei, TW
International Classification:
A61K 31/295, A61P 9/00, A61P 11/00, A61P 13/12, A61P 17/00, A61P 27/02
Abstract:
The present invention provides methods of treating soft tissue calcification in a subject, comprising a step of administering to said subject an effective amount of ferric organic compound, such as ferric citrate. The claimed methods may prevent, reverse, delay or stabilize soft tissue calcification in a subject having chronic kidney disease. Affected soft tissue calcification includes soft tissue calcification in the joint, skin, eye, in cardiovascular system such as heart valve, myocardium, coronary arteries and arteriole, or in internal organs such as kidney and lung.