DR. CHARLOTTE CUNNINGHAM-RUNDLES, M.D., PHD.
Osteopathic Medicine at 98 St, New York, NY

License number
New York 108611
Category
Osteopathic Medicine
Type
Allergy & Immunology
Address
Address
5 E 98Th St, New York, NY 10029
Phone
(212) 241-9767
(212) 534-0971 (Fax)
(212) 987-3100
(212) 731-5210 (Fax)

Organization information

See more information about CHARLOTTE CUNNINGHAM-RUNDLES at bizstanding.com

Charlotte Cunningham-Rundles MD,FAAAAI

5 E 98 St, New York, NY 10029

Industry:
Allergist, Internist
Phone:
(212) 241-9767 (Phone)
Charlotte F. Cunningham-Rundles

Professional information

Charlotte Cunningham-Rundles Photo 1

Charlotte Cunningham-Rundles, New York NY

Specialties:
Allergist, Internist, Pediatric Allergist, Pediatrician
Address:
5 East 98Th Street, New York, NY 10029
Education:
Medical School - MD, Columbia University
Bellevue Hospital Center (Residency - Internal Medicine)
New York University (PhD - Immunology)
Languages:
English, Spanish
Awards and Publications:
Chapel H, Cunningham-Rundles C. Update in understanding common variable immunodeficiency disorders (CVIDs) and the management of patients with these conditions. British journal of haematology 2009 Jun; 145(6)., Ballow M, Notarangelo L, Grimbacher B, Cunningham-Rundles C, Stein M, Helbert M, Gathmann B, Kindle G, Knight AK, Ochs HD, Sullivan K, Franco JL. Immunodeficiencies. Clinical and experimental immunology 2009 Dec; 158 Suppl 1., Chen K, Xu W, Wilson M, He B, Miller NW, Bengtén E, Edholm ES, Santini PA, Rath P, Chiu A, Cattalini M, Litzman J, B Bussel J, Huang B, Meini A, Riesbeck K, Cunningham-Rundles C, Plebani A, Cerutti A. Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. Nature immunology 2009 Aug; 10(8)., Ardeniz O, Cunningham-Rundles C. Granulomatous disease in common variable immunodeficiency. Clinical immunology (Orlando, Fla.) 2009 Nov; 133(2)., Ahn S, Cunningham-Rundles C. Role of B cells in common variable immune deficiency. Expert review of clinical immunology 2009 Sep; 5(5)., Agarwal S, Smereka P, Harpaz N, Cunningham-Rundles C, Mayer L. Characterization of immunologic defects in patients with common variable immunodeficiency (CVID) with intestinal disease. Inflammatory bowel diseases 2011 Jan; 17(1)., Ahn S, Cunningham-Rundles C. Role of B cells in common variable immune deficiency. Expert review of clinical immunology 2009 Sep; 5(5)., Best Doctors (New York Magazine - 2009), Cunningham-Rundles C. How I treat common variable immune deficiency. Blood 2010 Jul; 116(1)., Cunningham-Rundles C. Lung disease, antibodies and other unresolved issues in immune globulin therapy for antibody deficiency. Clinical and experimental immunology 2009 Sep; 157 Suppl 1., He B, Santamaria R, Xu W, Cols M, Chen K, Puga I, Shan M, Xiong H, Bussel JB, Chiu A, Puel A, Reichenbach J, Marodi L, Döffinger R, Vasconcelos J, Issekutz A, Krause J, Davies G, Li X, Grimbacher B, Plebani A, Meffre E, Picard C, Cunningham-Rundles C, Casanova JL, Cerutti A. The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nature immunology 2010 Sep; 11(9)., Isnardi I, Ng YS, Menard L, Meyers G, Saadoun D, Srdanovic I, Samuels J, Berman J, Buckner JH, Cunningham-Rundles C, Meffre E. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood 2010 Jun; 115(24)., Marron TU, Rohr K, Martinez-Gallo M, Yu J, Cunningham-Rundles C. TLR signaling and effector functions are intact in XLA neutrophils. Clinical immunology (Orlando, Fla.) 2010 Oct; 137(1)., Mc Guire PJ, Cunningham-Rundles C, Ochs H, Diaz GA. Oligoclonality, impaired class switch and B-cell memory responses in WHIM syndrome. Clinical immunology (Orlando, Fla.) 2010 Jun; 135(3)., Nakagawa Y, Iwatani K. Scanning thin-layer chromatography-liquid secondary ion mass spectrometry and its application for investigation of drug metabolites. Journal of chromatography 1991 Jan; 562(1-2)., Notarangelo LD, Fischer A, Geha RS, Casanova JL, Chapel H, Conley ME, Cunningham-Rundles C, Etzioni A, Hammartröm L, Nonoyama S, Ochs HD, Puck J, Roifman C, Seger R, Wedgwood J. Primary immunodeficiencies: 2009 update. The Journal of allergy and clinical immunology 2009 Dec; 124(6)., Wasserstrom H, Bussel J, Lim LC, Cunningham-Rundles C. Memory B cells and pneumococcal antibody after splenectomy. Journal of immunology (Baltimore, Md. : 1950) 2008 Sep; 181(5)., Yu JE, De Ravin SS, Uzel G, Landers C, Targan S, Malech HL, Holland SM, Cao W, Harpaz N, Mayer L, Cunningham-Rundles C. High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease. Clinical immunology (Orlando, Fla.) 2011 Jan; 138(1)., Yu JE, Knight AK, Radigan L, Marron TU, Zhang L, Sanchez-Ramón S, Cunningham-Rundles C. Toll-like receptor 7 and 9 defects in common variable immunodeficiency. The Journal of allergy and clinical immunology 2009 Aug; 124(2).
Board certifications:
American Board of Internal Medicine
About:
Dr. Cunningham-Rundles is the David S. Gottesman Professor of Immunology at the Mount Sinai School of Medicine in New York. She is a Professor of Medicine and Pediatrics, a member...


Charlotte Cunningham-Rundles Photo 2

Dr. Charlotte Cunningham-Rundles, New York NY - MD (Doctor of Medicine)

Specialties:
Internal Medicine
Address:
MOUNT SINAI MEDICAL CENTER
5 E 98Th St, New York 10029
(212) 831-1473 (Phone), (212) 241-9395 (Fax)
Ward F Cunningham-Rundles MD
240 E 68Th St, New York 10065
(212) 737-8973 (Phone)
Mt Sinai Adult Clincl Allrg/Imm
5 E 98Th St STE 11, New York 10029
(212) 241-0764 (Phone)
Certifications:
Internal Medicine, 1972
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Columbia University / College of Physicians And Surgeons
Graduated: 1969
Bellevue Hospital Center


Charlotte Cunningham-Rundles Photo 3

Oral Pharmaceutical Composition Containing A Polyethylene Glycol-Immunoglobulin G Conjugate For Reconstitution Of Secretory Immunity And Method Of Reconstituting Secretory Immunity

US Patent:
5169627, Dec 8, 1992
Filed:
Oct 28, 1991
Appl. No.:
7/783360
Inventors:
Charlotte Cunningham-Rundles - New York NY
Assignee:
Mount Sinai School of Medicine of the City University of New York - New York NY
International Classification:
A61K 39395, A61K 3944
US Classification:
424 8591
Abstract:
Polyethylene glycol serum immunoglobulin conjugates exhibit substantial rstance to degradation by intestinal enzyme while retaining their immuno-activity. Thus, PEG-IgG or PEG-IgA conjugates can be used as orally administered therapeutics to treat patients with gastrointestinal immunodeficiency to reconstitute secretory immunity. Preferred conjugates are made by reacting activated PEG and IgG in ratios of from 1:5 to 1:1000 such that less than about 27% of the IgG lysine residues are bonded to the PEG. The conjugates are advantageously formulated into a pharmaceutical composition comprising the conjugate and a pharmaceutically acceptable oral carrier. Particularly for administration to infants, a preferred oral carrier is milk.