CHARLES SFEIR
Dentist in Pittsburgh, PA
License number
Pennsylvania DS037092
Category
Dentistry
Type
Dentist
Address
Address
Pittsburgh, PA 15261
Organization information
See more information about CHARLES SFEIR at bizstanding.comCharles Sfeir DDS,DMD,PHD
3501 Ter St, Pittsburgh, PA 15213
Industry:
Dentists
Phone:
(412) 648-9100 (Phone)
Charles Sfeir
Professional information
Dr. Charles Sfeir, Pittsburgh PA - DDS (Doctor of Dental Surgery)
Specialties:
Periodontics
Address:
2413 Traci Dr STE 3189, Pittsburgh 15237
(412) 648-1949 (Phone)
(412) 648-1949 (Phone)
Languages:
English
Method Of Inducing Biomineralization Method Of Inducing Bone Regeneration And Methods Related Thereof
US Patent:
2007008, Apr 19, 2007
Filed:
Aug 19, 2004
Appl. No.:
10/568998
Inventors:
Charles Sfeir - Pittsburgh PA, US
Phil Campbell - Pittsburgh PA, US
Julie Jadlowiec - Pittsburgh PA, US
Prashant Kumta - Pittsburgh PA, US
Phil Campbell - Pittsburgh PA, US
Julie Jadlowiec - Pittsburgh PA, US
Prashant Kumta - Pittsburgh PA, US
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
Carnegie Mellon University - Pittsburgh PA
Carnegie Mellon University - Pittsburgh PA
International Classification:
A61K 38/17, A61K 48/00, C07K 14/47
US Classification:
514007000, 514044000, 530352000
Abstract:
A method of inducing biomineralization in a tissue, which method comprises administering to the tissue a source of Phosphophoryn (PP) in an amount sufficient to induce biomineralization; a method of treating tooth sensitivity or injured pulp tissue; a method of inducing differentiation of a cell into an osteogenic cell or odontogenic cell; a method of inducing bone or dentin regeneration; a method of inducing periodontal regeneration; a method of inducing differentiation of a cell into a cementoblast, osteoblast, or periodontal ligament cell; and a composition comprising a source of PP and a carrier.
Compositions And Devices Comprising Or Encoding The Run X2 Protein And Method Of Use
US Patent:
2003023, Dec 25, 2003
Filed:
May 13, 2003
Appl. No.:
10/437171
Inventors:
Bruce Doll - Wexford PA, US
Huihua Fu - Pittsburgh PA, US
Jeffrey Hollinger - Gibsonia PA, US
Charles Sfeir - Pittsburgh PA, US
Huihua Fu - Pittsburgh PA, US
Jeffrey Hollinger - Gibsonia PA, US
Charles Sfeir - Pittsburgh PA, US
International Classification:
A61K048/00, A61K038/17
US Classification:
424/093210, 424/426000, 514/012000, 514/044000
Abstract:
A pharmaceutical composition comprising in combination the Runx2 protein, a polynucleotide encoding the Runx2 protein, or a cell that has been transformed with a polynucleotide encoding Runx2 protein, in a pharmaceutically acceptable carrier, the carrier comprising a bio-compatible, biodegradable polymeric matrix. Another aspect of the present invention includes a device comprising the above-described pharmaceutical composition in combination with a sterile and substantially antigen-free, pre-shaped allograft or xenograft bone implant. Also contemplated herein is a method for repairing a bone defect comprising administering to a mammalian patient at the site in need of treatment a pharmaceutical composition, comprising in combination the Runx2 protein, a polynucleotide encoding the Runx2 protein, or a cell that has been transformed with a polynucleotide encoding Runx2 protein, in a pharmaceutically acceptable carrier wherein the carrier is a bio-compatible, biodegradable polymeric matrix.
Bone Substitute Compositions, Methods Of Preparation And Clinical Applications
US Patent:
8357364, Jan 22, 2013
Filed:
Sep 15, 2010
Appl. No.:
12/882554
Inventors:
Prashant Nagesh Kumta - Pittsburgh PA, US
Charles S. Sfeir - Pittsburgh PA, US
Abhijit Roy - Pittsburgh PA, US
Charles S. Sfeir - Pittsburgh PA, US
Abhijit Roy - Pittsburgh PA, US
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
A01N 63/00, A61F 2/10
US Classification:
424 937, 623 1611
Abstract:
The present invention relates to bone substitute compositions and methods of their preparation, and their use in a wide variety of clinical applications. The compositions include calcium phosphate, acidic calcium salt, basic calcium salt, sodium hydrogen phosphate and porogen. The compositions further include a mixing liquid. The compositions can optionally include biological signaling molecules and/or a growth compound. Further, the compositions can optionally include a plasticizer.
Method Of Manufacturing Hydroxyapatite And Uses Therefor In Delivery Of Nucleic Acids
US Patent:
7776600, Aug 17, 2010
Filed:
Jun 13, 2007
Appl. No.:
11/811992
Inventors:
Prashant N. Kumta - Pittsburgh PA, US
Charles Sfeir - Pittsburgh PA, US
Jeffrey Owen Hollinger - Pittsburgh PA, US
Daiwon Chol - Pittsburgh PA, US
Lee Weiss - Pittsburgh PA, US
Phil Campbell - Cranberry Township PA, US
Charles Sfeir - Pittsburgh PA, US
Jeffrey Owen Hollinger - Pittsburgh PA, US
Daiwon Chol - Pittsburgh PA, US
Lee Weiss - Pittsburgh PA, US
Phil Campbell - Cranberry Township PA, US
Assignee:
Carnegie Mellon University - Pittsburgh PA
International Classification:
C01B 25/12, A61L 27/32, A61F 2/00, A61K 31/715, C12N 15/00
US Classification:
435455, 427 227, 424423, 514 44, 423308
Abstract:
Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications.
Bone Substitute Compositions, Methods Of Preparation And Clinical Applications
US Patent:
2014000, Jan 2, 2014
Filed:
Sep 3, 2013
Appl. No.:
14/016387
Inventors:
Charles S. Sfeir - Pittsburgh PA, US
Abhijit Roy - Pittsburgh PA, US
Abhijit Roy - Pittsburgh PA, US
Assignee:
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION - PITTSBURGH PA
International Classification:
A61L 24/02
US Classification:
424400, 424602, 424 937
Abstract:
The present invention relates to bone substitute compositions and methods of their preparation, and their use in a wide variety of clinical applications. The compositions include calcium phosphate, acidic calcium salt, basic calcium salt, sodium hydrogen phosphate and porogen. The compositions further include a mixing liquid. The compositions can optionally include biological signaling molecules and/or a growth compound. Further, the compositions can optionally include a plasticizer.
Elastomeric, Polymeric Bone Engineering And Regeneration Compositions And Methods Of Making
US Patent:
2012014, Jun 7, 2012
Filed:
Dec 2, 2011
Appl. No.:
13/310033
Inventors:
Yadong Wang - Allison Park PA, US
Charles Sfeir - Pittsburgh PA, US
Charles Sfeir - Pittsburgh PA, US
Assignee:
University of Pittsburgh - Of The Commonwealth System Of Higher Education - Pittsburgh PA
International Classification:
A61F 2/28
US Classification:
623 2361
Abstract:
The invention relates to elastomeric, polymeric bone substitute compositions, methods for their preparation and their use in clinical applications, such as bone engineering and regeneration applications. The bone substitute compositions are osteoconductive in the absence of a biomolecule component. The bone substitute compositions are capable to regenerate bone in vitro or in vivo. The bone substitute compositions can be implanted into a bone defective site of a patient, and particularly, in the orthopedic, dental and caraniofacial areas of the patient.
Method Of Manufacturing Hydroxyapatite And Uses Therefor In Delivery Of Nucleic Acids
US Patent:
2003021, Nov 27, 2003
Filed:
Mar 19, 2003
Appl. No.:
10/393507
Inventors:
Prashant Kumta - Pittsburgh PA, US
Charles Sfeir - Pittsburgh PA, US
Jeffrey Hollinger - Pittsburgh PA, US
Daiwon Choi - Pittsburgh PA, US
Lee Weiss - Pittsburgh PA, US
Phil Campbell - Cranberry Township PA, US
Charles Sfeir - Pittsburgh PA, US
Jeffrey Hollinger - Pittsburgh PA, US
Daiwon Choi - Pittsburgh PA, US
Lee Weiss - Pittsburgh PA, US
Phil Campbell - Cranberry Township PA, US
International Classification:
A61K048/00, C01B025/26, A61F002/00
US Classification:
424/423000, 423/311000, 424/093210
Abstract:
Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications.
Bone Substitute Compositions, Methods Of Preparation And Clinical Applications
US Patent:
8557235, Oct 15, 2013
Filed:
Dec 11, 2012
Appl. No.:
13/711261
Inventors:
Prashant Nagesh Kumta - Pittsburgh PA, US
Charles S. Sfeir - Pittsburgh PA, US
Abhijit Roy - Pittsburgh PA, US
Charles S. Sfeir - Pittsburgh PA, US
Abhijit Roy - Pittsburgh PA, US
Assignee:
University of Pittsburgh—Of the Commonwealth System of Hihger Education - Pittsburgh PA
International Classification:
A01N 63/00, A61K 9/14, C12N 5/00
US Classification:
424 937, 424489, 435325
Abstract:
The present invention relates to bone substitute compositions and methods of their preparation, and their use in a wide variety of clinical applications. The compositions include calcium phosphate, acidic calcium salt, basic calcium salt, sodium hydrogen phosphate and porogen. The compositions further include a mixing liquid. The compositions can optionally include biological signaling molecules and/or a growth compound. Further, the compositions can optionally include a plasticizer.