CHARLES R ECK
Engineering in Shrewsbury, MA
License number
Massachusetts 18539
Issued Date
Apr 24, 1999
Type
Engineer in Training
Address
Address
Shrewsbury, MA 01545
Personal information
See more information about CHARLES R ECK at radaris.comName
Address
Phone
750 Davol St UNIT 212, Fall River, MA 02720
280 Elm St UNIT 2, S Dartmouth, MA 02748
Professional information
Aerosol Compositions And Methods
US Patent:
2007000, Jan 11, 2007
Filed:
Jun 28, 2006
Appl. No.:
11/477158
Inventors:
Charles Eck - Shrewsbury MA, US
Assignee:
Xemplar Pharmaceuticals, LLC - Fall River MA
International Classification:
A61K 9/14, A61K 31/202, A61L 9/04
US Classification:
424046000, 514560000
Abstract:
The present invention provides drug formulations and methods that comprise omega-3 and/or omega-6 fatty acids, and their ester derivatives (e.g., methyl, ethyl, isopropyl, etc.), which are soluble in non-CFC propellants. The addition of omega-3 or omega-6 fatty acids to the aerosol formulations also provides therapeutic benefits.
Separation Of Isomers Of Furo (3,4-C) Pyridine Derivatives
US Patent:
5047537, Sep 10, 1991
Filed:
Oct 18, 1990
Appl. No.:
7/598653
Inventors:
Andre Esanu - Paris, FR
Charles Eck - Shrewsbury MA
Charles Eck - Shrewsbury MA
Assignee:
Societe de Conseils de Recherches et d'Applications Scientifiques
(S.C.R.A.S.)
(S.C.R.A.S.)
International Classification:
C07D49148
US Classification:
546116
Abstract:
This invention relates to a method for the separation of stereoisomers of 7-hydroxy-furo[3,4-c]pyridine derivatives of the formula ##STR1## wherein R. sub. 3, R. sub. 4 and R. sub. 6 represent various substitutents, which comprises reacting a fully O-acetylated monosaccharide halogenide with a racemate of the selected 7-hydroxy-furo[3,4-c]pyridine derivative, to form the (+) and (-) (O-acetylated monosaccharide) (furo[3,4-c] pyridine 7-yl derivative) ethers, then separating the (+) and the (-) ethers by selective crystallization, in an hydroalcoholic medium, either of the acetylated forms or of the corresponding desacetylated forms and, finally, working up each of the separated derivatives by the usual routes. The compounds are known pharmaceuticals.
Asymmetric Synthesis Of Furo(3,4-C) Pyridine Derivatives
US Patent:
5043448, Aug 27, 1991
Filed:
Jul 26, 1990
Appl. No.:
7/557975
Inventors:
Charles Eck - Shrewsbury MA
Assignee:
Societe de Conseils de Recherches et d'Applications Scientifiques
International Classification:
C07D491048
US Classification:
546116
Abstract:
The invention relates to a method for the preparation of a non-racemic furo [3,4-c] pyridine derivatives of the formula I ##STR1## wherein R. sub. 1, R. sub. 2 and R. sub. 3 stand for various substitutents, comprising adding a concentrated strong acid to a solution of a non-racemic compound of the formula II ##STR2## in an amount sufficient to catalyze a deprotection/cyclodehydration. These compounds are known antihypertensives.
Resolution Of Furopyridine Enantiomers And Synthetic Precursors Thereof
US Patent:
5130252, Jul 14, 1992
Filed:
May 14, 1990
Appl. No.:
7/523238
Inventors:
Charles R. Eck - Shrewsbury MA
Paul C. Ahrens - Corvallis OR
Rae M. Saltzstein - McMinnville OR
Paul C. Ahrens - Corvallis OR
Rae M. Saltzstein - McMinnville OR
Assignee:
Synthetech, Inc. - Albany OR
International Classification:
C12P 702
US Classification:
435280
Abstract:
A method for resolving racemic mixtures of compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof that includes the steps of reacting the OR. sub. 3 group of either compound with an esterifying agent in the case where R. sub. 3 is H or a lower alkyl group; sujecting the compound to the action of an esterase capable of preferentially hydrolyzing either the (+) or (-) enantiomeric form of the compound; and separating the unhydrolyzed compound from the hydrolyzed compound.