DR. CHARLES MARTIN STROM, MD
Medical Practice at Ortega Hwy, San Juan Capistrano, CA
License number
California 643341
Category
Medical Practice
Type
Pediatrics
Address
Address
2
33608 Ortega Hwy, San Juan Capistrano, CA 92690
2939 Calle Gaucho, San Clemente, CA 92673
2939 Calle Gaucho, San Clemente, CA 92673
Phone
(949) 728-4701
(949) 728-4732 (Fax)
(949) 361-8745
(949) 728-4732 (Fax)
(949) 361-8745
Personal information
See more information about CHARLES MARTIN STROM at radaris.comName
Address
Phone
49 Chatham Pt, Alameda, CA 94502
2939 Calle Gaucho, San Clemente, CA 92673
1323 Olive St, West Hollywood, CA 90069
509 Bridge St, Folsom, CA 95630
1323 N Olive Dr, West Hollywood, CA 90069
Professional information
See more information about CHARLES MARTIN STROM at trustoria.com
Dr. Charles M Strom, San Juan Capistrano CA - MD (Doctor of Medicine)
Dr. Charles M Strom, San Juan Capistrano CA - MD (Doctor of Medicine)
Specialties:
Pediatrics, Clinical Biochemical Genetics, Clinical Genetics, Clinical Molecular Genetics
Address:
33608 Ortega Hwy, San Juan Capistrano 92675
(949) 728-4701 (Phone), (949) 728-4732 (Fax)
(949) 728-4701 (Phone), (949) 728-4732 (Fax)
Certifications:
Clinical Biochemical Genetics, 1987, Clinical Genetics, 1987, Clinical Molecular Genetics, 2010, Pediatrics, 1985
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
33608 Ortega Hwy, San Juan Capistrano 92675
Fallbrook Hospital
624 East Elder St, Fallbrook 92028
Saddleback Memorial Medical Center San Clemente
654 Camino De Los Mares, San Clemente 92673
Tri - City Medical Center
4002 Vista Way, Oceanside 92056
Fallbrook Hospital
624 East Elder St, Fallbrook 92028
Saddleback Memorial Medical Center San Clemente
654 Camino De Los Mares, San Clemente 92673
Tri - City Medical Center
4002 Vista Way, Oceanside 92056
Education:
Medical School
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
Graduated: 1979
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
Graduated: 1979
Charles Martin Strom, San Juan Capistrano CA
Charles Martin Strom, San Juan Capistrano CA
Specialties:
Pediatrics, Medical Genetics, Clinical Molecular Genetics, Clinical Biochemical Genetics, Clinical Genetics, M.D., Pediatric Medical Genetics
Work:
Quest Diagnostics Nichols Institute
33608 Ortega Hwy, San Juan Capistrano, CA 92675
33608 Ortega Hwy, San Juan Capistrano, CA 92675
Education:
University of Chicago (1979)
Subtractive Single Label Comparative Hybridization
Subtractive Single Label Comparative Hybridization
US Patent:
7892743, Feb 22, 2011
Filed:
Feb 25, 2009
Appl. No.:
12/392951
Inventors:
Renius X. Owen - Lake Elsinore CA, US
Charles M. Strom - San Clemente CA, US
Charles M. Strom - San Clemente CA, US
Assignee:
Quest Diagnostics Investments Incorporated - Wilmington DE
International Classification:
C12Q 1/68, C07H 21/02, C07H 21/04
US Classification:
435 6, 536 231, 536 243
Abstract:
Provided are methods of determining differences between nucleic acids in a test sample and a reference sample. In certain embodiments the methods are used for detecting and mapping chromosomal or genetic abnormalities associated with various diseases or with predisposition to various diseases, or to detecting the phenomena of large scale copy number variants. In particular, provided are advanced methods of performing array-based comparative hybridization that allow reproducibility between samples and enhanced sensitivity by using the same detectable label for both test sample and reference sample nucleic acids. Invention methods are useful for the detection or diagnosis of particular disease conditions such as cancer, and detecting predisposition to cancer based on detection of chromosomal or genetic abnormalities and gene expression level. Invention methods are also useful for the detection or diagnosis of hereditary genetic disorders or predisposition thereto, especially in prenatal samples. Moreover, invention methods are also useful for the detection or diagnosis of de novo genetic aberrations associated with post-natal developmental abnormalities.
Method To Detect Repeat Sequence Motifs In Nucleic Acid
Method To Detect Repeat Sequence Motifs In Nucleic Acid
US Patent:
2013011, May 9, 2013
Filed:
Feb 4, 2011
Appl. No.:
13/576740
Inventors:
Feras Hantash - Mission Viejo CA, US
Weimin Sun - Irvine CA, US
David C. Tsao - Hacienda Heights CA, US
Dana Marie Root - Orange CA, US
Charles M Strom - San Clemente CA, US
Weimin Sun - Irvine CA, US
David C. Tsao - Hacienda Heights CA, US
Dana Marie Root - Orange CA, US
Charles M Strom - San Clemente CA, US
Assignee:
QUEST DIAGNOSTICS INVESTMENTS INCORPORATED - Wilmington DE
International Classification:
C12Q 1/68
US Classification:
435 611, 702 19
Abstract:
Methods for determining the presence or absence of expansion of CGG repeat sequence in the FMR1 gene presence or absence of expansion of CCG repeat sequence in the FMR2 gene are provided. The methods are useful in identifying an individual with normal/intermediate, versus premutation or full mutation allele of FMR1 gene and FMR2 gene due to the expansion of CGG repeats and CCG repeats in the 5′-untranslated region respectively. The methods are also useful for screening newborns for fragile X syndrome or for screening women to determine heterozygosity status with full premutation of the CCG repeat tract. The methods are also useful in estimating the premutation and full mutation carrier frequency and estimating the prevalence of FXTAS AND FXPOI in a population. The methods are simple, rapid and require small amount of sample.
Substractive Single Label Comparative Hybridization
Substractive Single Label Comparative Hybridization
US Patent:
2009003, Feb 5, 2009
Filed:
Jul 30, 2007
Appl. No.:
11/830768
Inventors:
Renius Owen - Lake Elsinore CA, US
Charles M. Strom - San Clemente CA, US
Charles M. Strom - San Clemente CA, US
International Classification:
C12Q 1/68, C40B 30/04
US Classification:
435 6, 506 9
Abstract:
Provided are methods of determining differences between nucleic acids in a test sample and a reference sample. In certain embodiments the methods are used for detecting and mapping chromosomal or genetic abnormalities associated with various diseases or with predisposition to various diseases, or to detecting the phenomena of large scale copy number variants. In particular, provided are advanced methods of performing array-based comparative hybridization that allow reproducibility between samples and enhanced sensitivity by using the same detectable label for both test sample and reference sample nucleic acids. Invention methods are useful for the detection or diagnosis of particular disease conditions such as cancer, and detecting predisposition to cancer based on detection of chromosomal or genetic abnormalities and gene expression level. Invention methods are also useful for the detection or diagnosis of hereditary genetic disorders or predisposition thereto, especially in prenatal samples. Moreover, invention methods are also useful for the detection or diagnosis of de novo genetic aberrations associated with post-natal developmental abnormalities.
Nucleic Acid Size Detection Method
Nucleic Acid Size Detection Method
US Patent:
8163480, Apr 24, 2012
Filed:
Oct 5, 2006
Appl. No.:
11/544293
Inventors:
Donghui Huang - San Ramon CA, US
Charles M. Strom - San Clemente CA, US
Steven J. Potts - Flagstaff AZ, US
Jenny Ellen Rooke - Seattle WA, US
Charles M. Strom - San Clemente CA, US
Steven J. Potts - Flagstaff AZ, US
Jenny Ellen Rooke - Seattle WA, US
Assignee:
Quest Diagnostics Investments Incorporated - Wilmington DE
US Genomics, Inc. - Woburn MA
US Genomics, Inc. - Woburn MA
International Classification:
C12Q 1/68, C12P 19/34, C07H 21/02, C07H 21/04
US Classification:
435 61, 435 912, 536 231, 536 243
Abstract:
The present invention provides methods of determining the size of a particular nucleic acid segment of interest in a sample of nucleic acids through fragmentation of DNA, size fractionation, an optional second fragmentation, and identification using a marker sequence. In particular aspects, an expansion or reduction of tandem repeat sequences can be detected. In further aspects, carriers and individuals afflicted with fragile X syndrome or other diseases associated with tandem repeats can be distinguished from normal individuals.
Methods Of Detecting Tpmt Mutations
Methods Of Detecting Tpmt Mutations
US Patent:
7807359, Oct 5, 2010
Filed:
Dec 1, 2006
Appl. No.:
11/566174
Inventors:
Charles M. Strom - San Clemente CA, US
Feras M. Hantash - Dana Point CA, US
Feras M. Hantash - Dana Point CA, US
Assignee:
Quest Diagnostics Investments Incorporated - Wilmington DE
International Classification:
C12Q 1/68, C12P 19/34
US Classification:
435 6, 435 911, 435 912
Abstract:
Methods and compositions are described for use in the rapid and simultaneous screening of one or more samples for one or more mutations in the TPMT gene. The methods and compositions of the present invention can be used to rapidly determine if a mutation of the TPMT gene is present in the genome of a subject. Identifying which mutations are present in an individual allows the clinician to design an appropriate therapy using drugs metabolized by TPMT for that individual.
Nucleic Acid Size Detection Method
Nucleic Acid Size Detection Method
US Patent:
2010016, Jul 1, 2010
Filed:
Apr 11, 2007
Appl. No.:
12/444361
Inventors:
Donghui Huang - Irvine CA, US
Charles M. Strom - San Clemente CA, US
Steven J. Potts - San Diego CA, US
Jenny Ellen Rooke - Somerville MA, US
Charles M. Strom - San Clemente CA, US
Steven J. Potts - San Diego CA, US
Jenny Ellen Rooke - Somerville MA, US
International Classification:
G01N 27/26, C12Q 1/68, B01D 57/02
US Classification:
435 6, 204450, 204451
Abstract:
The present invention provides methods of determining the size of a particular nucleic acid segment of interest in a sample of nucleic acids through fragmentation of DNA, size fractionation, an optional second fragmentation, and identification using a marker sequence. In particular aspects, an expansion or reduction of tandem repeat sequences can be detected. In further aspects, carriers and individuals afflicted with fragile X syndrome or other diseases associated with tandem repeats can be distinguished from normal individuals.
Nucleic Acid Detection Combining Amplification With Fragmentation
Nucleic Acid Detection Combining Amplification With Fragmentation
US Patent:
2009018, Jul 16, 2009
Filed:
Feb 21, 2008
Appl. No.:
12/035356
Inventors:
Heather R. Sanders - Winchester CA, US
Kevin Z. Qu - Irvine CA, US
Charles M. Strom - San Clemente CA, US
Richard A. Bender - Dana Point CA, US
Kevin Z. Qu - Irvine CA, US
Charles M. Strom - San Clemente CA, US
Richard A. Bender - Dana Point CA, US
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
Provided herein are methods and compositions for detection of a nucleic acid target in a sample. The methods and compositions use primer directed amplification in conjunction with nucleic acid fragmentation. The methods have high sensitivity even in the presence of a large amount of non-target nucleic acid. Also provided are oligonucleotides and kits useful in the method. Exemplary nucleic acid targets are those with mutant gene sequence such as mutant sequence of the EGFR, APC, TMPRSS2, ERG and ETV1 genes.
Nucleic Acid Sequencing By Single-Base Primer Extension
Nucleic Acid Sequencing By Single-Base Primer Extension
US Patent:
2009008, Apr 2, 2009
Filed:
Sep 26, 2008
Appl. No.:
12/239573
Inventors:
Charles M. Strom - San Clemente CA, US
International Classification:
C40B 30/04, C12Q 1/68
US Classification:
506 9, 435 6
Abstract:
The present invention pertains to a method for determining a sequence of contiguous bases within a polynucleotide, the method relying on single-base primer extension using labeled dideoxynucleotide terminators. The primers are immobilized to solid supports (e.g. microspheres or two-dimensional arrays), allowing for the identification of the labeled terminator incorporated into each primer.