Inventors:
Charles L. Sawyers - New York NY, US
Michael E. Jung - Los Angeles CA, US
Charlie D. Chen - Los Angeles CA, US
Samedy Ouk - Costa Mesa CA, US
Derek Welsbie - Northridge CA, US
Chris Tran - New York NY, US
John Wongvipat - Nanuet NY, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 31/497, C07D 233/86, A61K 31/4166, C07D 401/04, A61K 31/4439, C07D 233/84, C07D 233/76, C07D 471/10, A61K 31/438, C07D 233/88, A61K 31/4164, C07D 241/04, A61P 35/00
US Classification:
51425405, 5483167, 514391, 5483014, 5462741, 514341, 546 20, 514278, 5483215, 514390, 544230
Abstract:
The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.