DR. CHARLES L PAMPLIN, M.D.
Osteopathic Medicine at Sleepy Hollow Rd, Chapel Hill, NC
License number
North Carolina 12JUNE1973
Category
Osteopathic Medicine
Type
Internal Medicine
Address
Address
608 Sleepy Hollow Rd, Chapel Hill, NC 27517
Phone
(919) 969-7007
Professional information
Oral Pediatric Trimethobenzamide Formulations And Methods
US Patent:
2004003, Feb 19, 2004
Filed:
Feb 6, 2003
Appl. No.:
10/360209
Inventors:
Jefferson Gregory - Bristol TN, US
Robert Bruns - Johnson City TN, US
Dean Cirotta - Webster NY, US
Thomas Rogers - Bristol TN, US
Charles Pamplin - Chapel Hill NC, US
Robert Bruns - Johnson City TN, US
Dean Cirotta - Webster NY, US
Thomas Rogers - Bristol TN, US
Charles Pamplin - Chapel Hill NC, US
Assignee:
King Pharmaceuticals, Inc. - Bristol TN
International Classification:
A61K031/165
US Classification:
514/622000
Abstract:
Oral pediatric trimethobenzamide compositions and methods for treating and controlling nausea and/or vomiting are disclosed in warm blooded animals, especially humans including children. The oral pediatric trimethobenzamide compositions and methods of the present invention are believed to be at least as effective as a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation when administered at a dose of about 100 mg. In addition, an oral pediatric composition containing about 120 mg of trimethobenzamide HCl is believed to be uniquely approximately bioequivalent to a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation when administered at a dose of about 100 mg.
Oral Trimethobenzamide Formulations And Methods
US Patent:
2004000, Jan 8, 2004
Filed:
Feb 6, 2003
Appl. No.:
10/360208
Inventors:
Jefferson Gregory - Bristol TN, US
Robert Bruns - Johnson City TN, US
Dean Cirotta - Webster NY, US
Thomas Rogers - Bristol TN, US
Charles Pamplin - Chapel Hill NC, US
Robert Bruns - Johnson City TN, US
Dean Cirotta - Webster NY, US
Thomas Rogers - Bristol TN, US
Charles Pamplin - Chapel Hill NC, US
Assignee:
King Pharmaceuticals, Inc. - Bristol TN
International Classification:
A61K031/165, A61K009/20
US Classification:
424/465000, 514/615000
Abstract:
Oral trimethobenzamide compositions and methods for treating and controlling nausea and/or vomiting are disclosed in warm blooded animals, especially humans including children. The oral trimethobenzamide compositions and methods of the present invention are at least as effective as a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation. In addition, an oral composition containing about 300 mg of trimethobenzamide HCl is uniquely approximately bioequivalent to a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation. The oral pediatric trimethobenzamide compositions and methods of the present invention are believed to be at least as effective as a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation when administered at a dose of about 100 mg. In addition, an oral pediatric composition containing about 120 mg of trimethobenzamide HCl is believed to be uniquely approximately bioequivalent to a 200 mg intramuscular (I.M.) trimethobenzamide HCl injectable formulation when administered at a dose of about 100 mg.
Controlled Release Pharmaceutical Compositions Of Liothyronine And Methods Of Making And Using The Same
US Patent:
2006024, Nov 2, 2006
Filed:
Mar 31, 2006
Appl. No.:
11/396420
Inventors:
Martin Beasley - Cary NC, US
David Hause - Carrboro NC, US
Irwin Klein - Manhasset NY, US
Charles Pamplin - Chapel Hill NC, US
David Reynolds - Durham NC, US
Kevin Sills - Apex NC, US
David Hause - Carrboro NC, US
Irwin Klein - Manhasset NY, US
Charles Pamplin - Chapel Hill NC, US
David Reynolds - Durham NC, US
Kevin Sills - Apex NC, US
International Classification:
A61K 31/198, A61K 9/22
US Classification:
424468000, 514567000
Abstract:
This invention relates to sustained release pharmaceutical compositions comprising liothyronine, or a salt or derivative thereof. Additionally, the present invention is directed to methods of manufacture and methods of using the pharmaceutical compositions of the present invention.