Inventors:
Andreas G. Bader - Austin TX, US
Mike W. Byrom - Austin TX, US
Lubna Patrawala - Austin TX, US
Charles D. Johnson - Austin TX, US
David Brown - Austin TX, US
Assignee:
ASURAGEN, INC. - Austin TX
International Classification:
A61K 31/7105, C12N 5/06, C12Q 1/68
Abstract:
The present invention concerns methods and compositions for identifying genes or genetic pathways modulated by miR-15, miR-26, miR-31, miR-145, miR-147, miR-188, miR-215, miR-216, miR-331, mmu-miR-292-3p, and using nucleic acid comprising all or part of the miR-15, miR-26, miR-31, miR-145, miR-147, miR-188, miR-215, miR-216, miR-331, mmu-miR-292-3p sequences to modulate a gene or gene pathway, using this profile in assessing the condition of a patient and/or treating the patient with an appropriate miRNA.