Inventors:
Jatin Patel - West Windsor NJ, US
Charles Frost - Yardley PA, US
Jingpin Jia - Belle Mead NJ, US
Chandra Vemavarapu - Hillsborough NJ, US
Assignee:
PFIZER, INC. - New York NY
BRISTOL-MYERS SQUIBB COMPANY - Princeton NJ
International Classification:
A61K 31/4545, A61P 7/02, A61K 9/14
Abstract:
Compositions comprising crystalline apixaban particles having a Dequal to or less than 89 μm, and a pharmaceutically acceptable carrier, are substantially bioequivalent and can be used to for the treatment and/or prophylaxis of thromboembolic disorders.