Inventors:
Jitendra Ramanlal Dave - Gaithersburg MD, US
Changping Yao - Gaithersburg MD, US
Anthony Joseph Williams - Middletown MD, US
Xi-Chun May - Laurel MD, US
Frank Casper Tortella - Columbia MD, US
Ka-Wang Kevin Wang - Gainsville FL, US
Ronald Lawrence Hayes - Gainsville FL, US
International Classification:
C40B 40/10, C40B 40/00
Abstract:
A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury. Detection of EMAP-II can be done in brain tissue, biofluids such as cerebrospinal fluid or blood (including plasma and serum)