Inventors:
Sydney Welt - New York NY
Chaitanya R. Divgi - New York NY
Samual Yeh - New York NY
Lloyd J. Old - New York NY
Herbert F. Oettgen - New Canaan CT
Francisco X. Real - Barcelona, ES
Junichi Sakamoto - Chikusaku Nagoya, JP
Assignee:
Sloan-Kettering Institute for Cancer Research - New York NY
International Classification:
A61K 4300, A61K 4900, A61K 3514, G01N 33566
Abstract:
This invention provides a method of imaging a colorectal carcinoma lesion in a human patient which comprises administering to the patient a monoclonal antibody capable of binding to a cell surface antigen associated with the colorectal carcinoma lesion and which is labeled with an imaging agent under conditions so as to form a complex between the monoclonal antibody and the cell surface antigen, imaging any complex so formed, and thereby imaging the colorectal carcinoma lesion.
This invention also provides a monoclonal antibody designated AS 33 (ATCC Accession No. HB 8779) and the hybridoma which produces it.